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1. (WO2018106656) TRUNCATED LPMO ENZYMES AND USE THEREOF
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Pub. No.: WO/2018/106656 International Application No.: PCT/US2017/064651
Publication Date: 14.06.2018 International Filing Date: 05.12.2017
IPC:
C12N 9/02 (2006.01) ,C12P 19/04 (2006.01) ,C12N 9/42 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9
Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
02
Oxidoreductases (1.), e.g. luciferase
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
19
Preparation of compounds containing saccharide radicals
04
Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9
Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
14
Hydrolases (3.)
24
acting on glycosyl compounds (3.2)
42
acting on beta-1, 4-glucosidic bonds, e.g. cellulase
Applicants:
DANISCO US INC [US/US]; 925 Page Mill Road Palo Alto, CA 94304, US
Inventors:
LAM, Anna, May; US
LIU, Chuanbin; US
TORRES PAZMINO, Daniel, Esteban; NL
DOUGLAS, Nicholai, Rainsong; US
KIM, Steven, Sungjin; US
KAPER, Thijs; US
KARKEHABADI, Saeid; SE
HANSSON, Henrik; SE
SANDGREN, Mats; SE
Agent:
CHESIRE, Dennis R.; US
Priority Data:
62/430,54006.12.2016US
62/510,37624.05.2017US
Title (EN) TRUNCATED LPMO ENZYMES AND USE THEREOF
(FR) ENZYMES DE LPMO TRONQUÉS ET LEUR UTILISATION
Abstract:
(EN) Disclosed herein are truncated lytic polysaccharide mono-oxygenase (LPMO) enzymes lacking a carbohydrate-binding module (CBM). Further disclosed, for example, are compositions comprising these enzymes, and methods of producing and using them. In addition, combinations of truncated LPMOs and full-length LPMOs are disclosed to have improved cellulase-enhancing activities.
(FR) L'invention concerne des enzymes de polysaccharides mono-oxygénase lytiques (LPMO) tronqués, dépourvues d'un module de liaison aux glucides (CBM). Elle concerne également, par exemple, des compositions comprenant ces enzymes et des procédés de production et d'utilisation de celles-ci. Elle concerne en outre des combinaisons de LPMO tronqués et de LPMO pleine longueur pouvant présenter une activité améliorée de facilitation de la cellulase.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)