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1. (WO2018106606) PYRIMIDINE COMPOUNDS CONTAINING ACIDIC GROUPS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/106606 International Application No.: PCT/US2017/064541
Publication Date: 14.06.2018 International Filing Date: 04.12.2017
IPC:
C07D 403/10 (2006.01) ,C07D 239/49 (2006.01) ,A61K 31/505 (2006.01) ,A61K 31/506 (2006.01) ,A61P 29/00 (2006.01)
Applicants: APROS THERAPEUTICS, INC.[US/US]; 10210 Campus Point Drive, Suite 150 San Diego, California 92121, US
Inventors: WU, Tom Yao-Hsiang; US
Agent: TONG, Connie C.; US
BLINKA, Thomas A.; US
Priority Data:
62/430,18305.12.2016US
62/532,23013.07.2017US
Title (EN) PYRIMIDINE COMPOUNDS CONTAINING ACIDIC GROUPS
(FR) COMPOSÉS DE PYRIMIDINE CONTENANT DES GROUPES ACIDES
Abstract:
(EN) The present disclosure relates to a class of pyrimidine derivatives having immunomodulating properties that act via TLR7 which are useful in the treatment of viral infections and cancers.
(FR) La présente invention concerne une classe de dérivés de pyrimidine ayant des propriétés d'immunomodulation qui agissent par l'intermédiaire de TLR7 et sont utiles dans le traitement d'infections virales et de cancers.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)