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1. (WO2018106594) FAT DROPLETS IN RETINA AND OPTIC NERVE AS A DIAGNOSTIC MARKER FOR NEURODEGENERATION AND GLAUCOMA IN HUMANS
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Pub. No.: WO/2018/106594 International Application No.: PCT/US2017/064504
Publication Date: 14.06.2018 International Filing Date: 04.12.2017
IPC:
A61B 3/12 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
3
Apparatus for testing the eyes; Instruments for examining the eyes
10
Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions
12
for looking at the eye fundus, e.g. ophthalmoscopes
Applicants:
THE JACKSON LABORATORY [US/US]; 600 Main Street Bar Harbor, ME 04609, US
Inventors:
JOHN, Simon, W., M.; US
WILLIAMS, Peter, Alexander; US
Agent:
ANDERSON, MaryDilys S.; US
Priority Data:
62/429,95005.12.2016US
Title (EN) FAT DROPLETS IN RETINA AND OPTIC NERVE AS A DIAGNOSTIC MARKER FOR NEURODEGENERATION AND GLAUCOMA IN HUMANS
(FR) GOUTTELETTES DE MATIÈRES GRASSES DANS LA RÉTINE ET LE NERF OPTIQUE UTILISÉES COMME MARQUEUR DE DIAGNOSTIC POUR UNE NEURODÉGÉNÉRESCENCE ET UN GLAUCOME CHEZ L'HOMME
Abstract:
(EN) The present invention relates to the use of lipid / fat droplet deposits in retinas of a human subject as a biomarker for diagnosing, prognosing, and/or monitoring retinal and/or optic nerve neurodegeneration with or without an elevated intraocular pressure in glaucoma.
(FR) La présente invention concerne l'utilisation de dépôts de gouttelettes de lipides/matières grasses dans les rétines d'un sujet humain comme biomarqueur pour diagnostiquer, pronostiquer et/ou surveiller une neurodégénérescence de la rétine et/ou du nerf optique avec ou sans pression intraoculaire élevée conduisant à un glaucome.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)