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1. (WO2018106588) ANTI-TIM-3 ANTIBODIES FOR COMBINATION WITH ANTI-PD-1 ANTIBODIES

Pub. No.:    WO/2018/106588    International Application No.:    PCT/US2017/064480
Publication Date: Fri Jun 15 01:59:59 CEST 2018 International Filing Date: Tue Dec 05 00:59:59 CET 2017
IPC: C07K 16/28
A61P 35/00
A61K 39/00
Applicants: ELI LILLY AND COMPANY
INNOVENT BIOLOGICS (SUZHOU) CO. LTD.
Inventors: LI, Yiwen
ZHANG, Yi
Title: ANTI-TIM-3 ANTIBODIES FOR COMBINATION WITH ANTI-PD-1 ANTIBODIES
Abstract:
The present invention relates to antibodies that bind human T-cell immunoglobulin- and mucin-domain-containing protein-3 (Tim-3), and may be useful for treating solid and hematological tumors in combination with anti-human PD-1 antibodies, chemotherapy, and ionizing radiation.