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1. (WO2018106529) ANTI-TIM-3 ANTIBODIES FOR COMBINATION WITH ANTI-PD-L1 ANTIBODIES
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/106529    International Application No.:    PCT/US2017/064207
Publication Date: 14.06.2018 International Filing Date: 01.12.2017
IPC:
C07K 16/28 (2006.01), A61K 39/395 (2006.01), A61K 39/00 (2006.01)
Applicants: ELI LILLY AND COMPANY [US/US]; Lilly Corporate Center Indianapolis, Indiana 46285 (US)
Inventors: LI, Yiwen; (US).
ZHANG, Yi; (US)
Agent: GARCIA, Carlos, A.; (US).
BARRETT, Brian P.; (US)
Priority Data:
62/431,485 08.12.2016 US
Title (EN) ANTI-TIM-3 ANTIBODIES FOR COMBINATION WITH ANTI-PD-L1 ANTIBODIES
(FR) ANTICORPS ANTI-TIM-3 POUR COMBINAISON AVEC DES ANTICORPS ANTI-PD-L1
Abstract: front page image
(EN)The present invention relates to antibodies that bind human T-cell immunoglobulin- and mucin-domain-containing protein-3 (Tim-3), and may be useful for treating solid and hematological tumors in combination with anti-human PD-L1 antibodies, chemotherapy, and ionizing radiation.
(FR)La présente invention concerne des anticorps qui se lient à la protéine-3 (Tim-3) contenant le domaine de la mucine et de l'immunoglobuline de lymphocytes T humaine, et peut être utile pour traiter des tumeurs solides et hématologiques en combinaison avec des anticorps anti-PD-L1 d'origine humaine, la chimiothérapie et un rayonnement ionisant.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)