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1. (WO2018106184) APPLICATION OF MULTI-KINASE INHIBITOR

Pub. No.:    WO/2018/106184    International Application No.:    PCT/SG2017/050598
Publication Date: Fri Jun 15 01:59:59 CEST 2018 International Filing Date: Wed Dec 06 00:59:59 CET 2017
IPC: A61K 31/4706
A61K 31/4035
A61K 31/407
A61P 27/02
C07D 215/20
C07D 215/44
C07D 215/54
C07D 209/48
Applicants: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
SINGAPORE HEALTH SERVICES PTE LTD
Inventors: CHUA, Boon Tin
VELUCHAMY AMUTHA, Barathi
WANG, Xiaomeng
Title: APPLICATION OF MULTI-KINASE INHIBITOR
Abstract:
Disclosed is the use of heterocylic compounds of Formula (I) in the treatment of eye diseases, such as a retinal and/or choroid angiogenic disease selected from the group consisting of age-related macular degeneration (AMD), diabetic retinopathy (DR), glaucoma, polypoidal choroidal vasculopathy (PCV), and retinopathy of prematurity (ROP).