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1. (WO2018106062) COMPOSITION COMPRISING AP OR NM FOR PREVENTION OR TREATMENT OF INFLAMMATORY DISEASE
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/106062 International Application No.: PCT/KR2017/014391
Publication Date: 14.06.2018 International Filing Date: 08.12.2017
IPC:
A61K 35/583 (2015.01) ,A61K 8/98 (2006.01) ,A61Q 19/00 (2006.01)
[IPC code unknown for A61K 35/583]
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8
Cosmetics or similar toilet preparations
18
characterised by the composition
96
containing materials, or derivatives thereof, of undetermined constitution
98
of animal origin
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
Q
SPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
19
Preparations for care of the skin
Applicants: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION[KR/KR]; 206, World cup-ro, Yeongtong-gu Suwon-si Gyeonggi-do 16499, KR
Inventors: SOHN, Seong Hyang; KR
Agent: KIM, Tae Sun; KR
Priority Data:
10-2016-016786709.12.2016KR
10-2016-016786809.12.2016KR
Title (EN) COMPOSITION COMPRISING AP OR NM FOR PREVENTION OR TREATMENT OF INFLAMMATORY DISEASE
(FR) COMPOSITION COMPRENANT AP OU NM POUR LA PRÉVENTION OU LE TRAITEMENT D’UNE MALADIE INFLAMMATOIRE
(KO) AP 또는 NM를 포함하는 염증성 질환의 예방 또는 치료용 조성물
Abstract:
(EN) Th present invention relates to a composition comprising snake venom for the prevention or treatment of an inflammatory disease. More specifically, the present invention relates to a pharmaceutical composition comprising Agkistrodon piscivorus piscivorus (AP) or Naja melanoleuca (NM) as an active ingredient for the prevention or treatment of an inflammatory disease, a quasi-drug composition, and a method for the prevention or treatment of an inflammatory disease, the method comprising a step for administering the composition to a subject or a step for coating the composition on the skin of a subject. The composition comprising snake venom for the prevention or treatment of an inflammatory disease of the present invention has excellent skin ulcer treatment efficacy by increasing the expression of C-C chemokine receptor type 1 (CCR1) in skin ulcer-induced mice, and thus can be advantageously used through the application to medical products including an externally-applied dermal preparation for the treatment of a skin ulcer, especially the treatment of Behcet's disease or Buerger's disease.
(FR) La présente invention concerne une composition comprenant du venin de serpent pour la prévention ou le traitement d’une maladie inflammatoire. Plus spécifiquement, la présente invention concerne une composition pharmaceutique comprenant Agkistrodon piscivorus piscivorus (AP) ou Naja melanoleuca (NM) en tant que substance active pour la prévention ou le traitement d’une maladie inflammatoire, d’une composition de quasi-médicament, et un procédé de prévention ou de traitement d’une maladie inflammatoire, le procédé comprenant une étape d’administration de la composition à un sujet ou une étape de revêtement de la composition sur la peau d’un sujet. La composition comprenant du venin de serpent pour la prévention ou le traitement d’une maladie inflammatoire de la présente invention présente une excellente efficacité de traitement des ulcères cutanés en augmentant l’expression du récepteur de chimiokine C-C de type 1 (CCR1) chez des souris avec ulcère cutané induit, et peut ainsi être avantageusement utilisée par l’application à des produits médicaux comprenant une préparation dermique à application externe pour le traitement d’un ulcère cutané, en particulier le traitement de la maladie de Behçet ou de la maladie de Buerger.
(KO) 본 발명은 뱀독을 포함하는 염증성 질환의 예방 또는 치료용 조성물에 관한것이다. 보다 구체적으로, 본 발명은 AP(Agkistrodon piscivorus piscivorus) 또는 NM(Naja melanoleuca)를 유효성분으로 포함하는 염증성 질환의 예방 또는 치료용 약제학적 조성물, 의약외품 조성물, 및 상기 조성물을 개체에 투여하는 단계 또는 개체의 피부에 도포하는 단계를 포함하는 염증성 질환의 예방 또는 치료 방법에 관한 것이다. 본 발명의 뱀독을 포함하는 염증성 질환의 예방 또는 치료용 조성물은 피부 궤양이 유발된 마우스에서 C-C 케모카인 수용체(C-C chemokine receptor type 1, CCR1)의 발현을 증가시킴으로써 피부 궤양 치료 효능이 뛰어나, 피부 궤양 치료, 특히 베체트병(Behcet's disease) 또는 버거씨병(Buerger's disease)의 치료를 위한 피부 외용제를 비롯한 의약품 등에 적용되어 유용하게 사용될 수 있을 것이다.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)