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1. (WO2018105998) COMPOSITION FOR PREVENTING AND TREATING MALE INFERTILITY, CONTAINING FLAVONOID DERIVATIVE COMPOUND AS ACTIVE INGREDIENT, AND USE THEREOF
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Pub. No.: WO/2018/105998 International Application No.: PCT/KR2017/014176
Publication Date: 14.06.2018 International Filing Date: 06.12.2017
IPC:
A61K 31/7048 (2006.01) ,A61K 31/352 (2006.01) ,A23L 33/10 (2016.01)
Applicants: INDUSTRIAL COOPERATION FOUNDATION CHONBUK NATIONAL UNIVERSITY[KR/KR]; 567, Baekje-daero, Deokjin-gu Jeonju-si Jeollabuk-do 54896, KR
Inventors: PARK, Jong Kwan; KR
Agent: SHIN, Dong In; KR
Priority Data:
10-2016-016652608.12.2016KR
Title (EN) COMPOSITION FOR PREVENTING AND TREATING MALE INFERTILITY, CONTAINING FLAVONOID DERIVATIVE COMPOUND AS ACTIVE INGREDIENT, AND USE THEREOF
(FR) COMPOSITION DESTINÉE À LA PRÉVENTION ET AU TRAITEMENT DE L'INFERTILITÉ MASCULINE, COMPRENANT UN COMPOSÉ DÉRIVÉ DE FLAVONOÏDES EN TANT QUE PRINCIPE ACTIF, ET SON UTILISATION
(KO) 플라보노이드 유도체 화합물을 유효성분으로 함유하는 남성 불임증 예방 및 치료용 조성물 및 이의 용도
Abstract: front page image
(EN) The present invention relates to a composition for preventing and treating male infertility, containing a flavonoid compound as an active ingredient. Through an in vitro sperm movement promoting effect evaluation method experiment for investigating the effect of the flavonoid derivative compound of the present invention on changes in the sperm count and mobility of human and porcine semen, it was confirmed that samples of the present invention show increased sperm mobility in the in vitro experiment with the human and porcine semen. Accordingly, the composition can be useful for a pharmaceutical composition, a health functional food and a health supplemental food for preventing and treating male infertility.
(FR) La présente invention concerne une composition destinée à la prévention et au traitement de l'infertilité masculine, comprenant un composé de flavonoïdes en tant que principe actif. Par l'intermédiaire d'une expérience de procédé d'évaluation d'effet favorisant le mouvement des spermatozoïdes in vitro destinée à étudier l'effet du composé dérivé de flavonoïdes de la présente invention sur des changements du nombre de spermatozoïdes et de la mobilité du sperme humain et porcin, il a été confirmé que les échantillons de la présente invention font preuve d'une mobilité accrue des spermatozoïdes dans l'expérience in vitro avec le sperme humain et porcin. Par conséquent, la composition peut servir à une composition pharmaceutique, un aliment fonctionnel de santé et un complément alimentaire de santé destinés à la prévention et au traitement de l'infertilité masculine.
(KO) 본 발명은 플라보노이드 화합물을 유효성분으로 함유하는 남성 불임증 예방 및 치료용 조성물에 대한 것이다. 본 발명의 플라보노이드 유도체 화합물을 대상으로 사람과 돼지정액의 정자수와 운동성 변화에 미치는 영향을 알아보기 위한 시험관내 (In vitro) 정자 운동 증진 효능 평가법 실험을 통하여 본 발명의 시료들이 사람과 돼지정액의 in vitro 실험에서 정자 운동성이 증가함을 확인함으로서, 상기 조성물을 남성불임증의 예방 및 치료용 약학조성물, 건강기능식품 및 건강보조식품에 유용하게 이용될 수 있다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)