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1. (WO2018105982) IMPROVED PURIFICATION METHOD OF RECOMBINANT PROTEIN

Pub. No.:    WO/2018/105982    International Application No.:    PCT/KR2017/014123
Publication Date: Fri Jun 15 01:59:59 CEST 2018 International Filing Date: Wed Dec 06 00:59:59 CET 2017
IPC: C07K 1/14
C07K 1/18
C07K 1/20
C07K 1/34
C07K 1/36
C07K 14/61
Applicants: HANMI PHARM. CO., LTD.
한미약품 주식회사
Inventors: KIM, Min Young
김민영
PARK, Hyong Jhun
박형준
KIM, Dae Jin
김대진
JUNG, Sung Youb
정성엽
Title: IMPROVED PURIFICATION METHOD OF RECOMBINANT PROTEIN
Abstract:
The present invention relates to a method for purifying a recombinant protein from recombinant E. coli at high yield and purity without using an additional activation process and including variants and to a method for purifying a recombinant protein at high yield and purify from recombinant E. coli which expresses the recombinant protein in the periplasm thereof.