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1. (WO2018105982) IMPROVED PURIFICATION METHOD OF RECOMBINANT PROTEIN
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/105982 International Application No.: PCT/KR2017/014123
Publication Date: 14.06.2018 International Filing Date: 05.12.2017
IPC:
C07K 1/14 (2006.01) ,C07K 1/18 (2006.01) ,C07K 1/20 (2006.01) ,C07K 1/34 (2006.01) ,C07K 1/36 (2006.01) ,C07K 14/61 (2006.01)
Applicants: HANMI PHARM. CO., LTD.[KR/KR]; 214, Muha-ro, Paltan-myeon, Hwaseong-si, Gyeonggi-do 18536, KR
Inventors: KIM, Min Young; KR
PARK, Hyong Jhun; KR
KIM, Dae Jin; KR
JUNG, Sung Youb; KR
Agent: SON, Min; KR
Priority Data:
10-2016-016462005.12.2016KR
10-2017-012642128.09.2017KR
Title (EN) IMPROVED PURIFICATION METHOD OF RECOMBINANT PROTEIN
(FR) PROCÉDÉ DE PURIFICATION AMÉLIORÉ DE PROTÉINE RECOMBINANTE
(KO) 재조합 단백질의 개선된 정제 방법
Abstract: front page image
(EN) The present invention relates to a method for purifying a recombinant protein from recombinant E. coli at high yield and purity without using an additional activation process and including variants and to a method for purifying a recombinant protein at high yield and purify from recombinant E. coli which expresses the recombinant protein in the periplasm thereof.
(FR) La présente invention concerne un procédé de purification d'une protéine recombinante à partir d'E. coli recombinante à un haut rendement et une pureté élevée sans utiliser de processus d'activation supplémentaire et comprenant des variants et un procédé de purification d'une protéine recombinante à un rendement et une purification élevés à partir d'E. coli recombinante qui exprime la protéine recombinante dans son périplasme.
(KO) 본 발명은 재조합 대장균으로부터 재조합 단백질을 별도의 활성화 공정 없이 변형체를 포함하지 않으면서 고수율 및 고순도로 정제하는 방법에 관한 것으로, 재조합 단백질을 페리플라즘 내에서 발현하는 재조합 대장균으로부터 재조합 단백질을 고수율 및 고순도로 정제하는 방법에 관한 것이다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)