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1. (WO2018105858) LINKING PEPTIDE FOR BIOMOLECULE BINDING
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/105858 International Application No.: PCT/KR2017/009386
Publication Date: 14.06.2018 International Filing Date: 28.08.2017
IPC:
C07K 7/08 (2006.01) ,C07K 14/315 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
7
Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04
Linear peptides containing only normal peptide links
08
having 12 to 20 amino acids
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
195
from bacteria
315
from Streptococcus (G), e.g. Enterococci
Applicants: INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY[KR/KR]; 77, Yongbong-ro Buk-gu Gwangju 61186, KR
Inventors: RHEE, Joon Haeng; KR
LEE, Shee Eun; KR
JEONG, Kwang Joon; KR
TAN, Wenzhi; KR
KIM, Soo Young; KR
Agent: YOON, Dae Woong; KR
Priority Data:
10-2016-016515206.12.2016KR
Title (EN) LINKING PEPTIDE FOR BIOMOLECULE BINDING
(FR) PEPTIDE DE LIAISON LIANT DES BIOMOLÉCULES
(KO) 생체분자 결합용 연결펩티드
Abstract:
(EN) The present invention relates to a linking peptide for biomolecule binding, and provides a linking peptide for binding a biomolecule to a terminal thereof by using a part of a PspA protein, which is a surface protein of Streptococcus pneumoniae, thereby being usable in the preparation of a fusion protein. According to the present invention, the activity of antibodies linked to both terminals of the linking peptide is enhanced when a fusion protein is prepared, thereby enabling the same to be effectively used as a linking peptide for biomolecules.
(FR) La présente invention concerne un peptide de liaison liant des biomolécules et fournit un peptide de liaison pour lier une biomolécule à un terminal de celle-ci à l'aide d'une partie d'une protéine PspA, qui est une protéine de surface de Streptococcus pneumoniae, d'où son utilisation dans la préparation d'une protéine de fusion. Selon la présente invention, l'activité d'anticorps liés aux deux extrémités du peptide de liaison est améliorée lorsqu'une protéine de fusion est préparée, ce qui permet de l'utiliser efficacement en tant que peptide de liaison pour des biomolécules.
(KO) 본 발명은 생체분자 결합용 연결펩티드에 관한 것으로서, 폐렴구균의 표면단백질인 PspA 단백질의 일부를 이용하여 말단에 생체분자를 결합시킴으로써 융합단백질 제조용으로 이용할 수 있는 연결펩티드를 제공한다. 상기와 같은 본 발명에 따르면, 융합단백질을 제조할 경우 상기 연결펩티드의 양 말단에 연결된 항체의 활성이 증진되므로 이를 효과적으로 생체분자의 연결펩티드로서 이용할 수 있는 효과가 있다.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)