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1. (WO2018105805) METHOD FOR ISOLATING ISLET OF NEWBORN PIG
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/105805    International Application No.:    PCT/KR2017/000273
Publication Date: 14.06.2018 International Filing Date: 09.01.2017
IPC:
C12N 5/071 (2010.01)
Applicants: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION [KR/KR]; (Sillim-dong) 1, Gwanak-ro Gwanak-gu Seoul 08826 (KR)
Inventors: AHN, Curie; (KR).
LEE, Eun Mi; (KR).
ZAHID, Alam Md; (KR)
Agent: CHO, Young Hyun; (KR)
Priority Data:
10-2016-0166487 08.12.2016 KR
Title (EN) METHOD FOR ISOLATING ISLET OF NEWBORN PIG
(FR) PROCÉDÉ D'ISOLEMENT D'UN ÎLOT DE PORC NOUVEAU-NÉ
(KO) 신생돼지의 췌도 분리 방법
Abstract: front page image
(EN)The present invention relates to a method for isolating an islet from a newborn pig and, specifically, to a method for isolating an islet of a newborn pig, the method comprising the steps of: (a) extracting an islet from a newborn pig; (b) injecting an enzyme into an extracted pancreas; and (c) inducing the activation of the enzyme. The use of the method for isolating an islet according to the present invention can isolate a high-quality islet from a newborn pig at high efficiency, and thus can lead to not only the utilization as an islet isolation technique for xenotransplantation but also the development of techniques for isolation, culture, and quality analysis of an islet of a newborn pig, and therefore, the method according to the present invention can be widely utilized in the biomedical field, such as diabetes treatment.
(FR)La présente invention concerne un procédé d'isolement d'un îlot de porc nouveau-né et, plus spécifiquement, un procédé d'isolement d'un îlot de porc nouveau-né, le procédé comprenant les étapes suivantes : (a) extraire un îlot d'un porc nouveau-né ; (b) injecter une enzyme dans le pancréas ayant fait l'objet de l'extraction ; et (c) induire l'activation de l'enzyme. L'utilisation du procédé d'isolement d'un îlot selon la présente invention permet d'isoler un îlot de grande qualité d'un porc nouveau-né à un rendement élevé, et peut ainsi conduire à non seulement son utilisation à titre de technique d'isolement d'îlots pour xénogreffe, mais aussi au développement de techniques d'isolement, de culture et d'analyse de qualité d'un îlot de porc nouveau-né, et par conséquent, le procédé selon la présente invention peut être largement utilisé dans le domaine biomédical, tel que le traitement du diabète.
(KO)본 발명은 신생돼지로부터 췌도를 분리하는 방법에 관한 것으로, 구체적으로 (a) 신생돼지로부터 췌도를 적출하는 단계; (b) 적출한 췌장에 효소를 주입하는 단계; 및 (c) 효소의 활성화를 유도하는 단계를 포함하는 신생돼지의 췌도 분리 방법에 관한 것으로, 본 발명에 따른 췌도의 분리 방법을 이용하면 신생돼지로부터 높은 효율로 양질의 췌도를 분리해낼 수 있는바, 이종간 이식을 위한 췌도 분리 기술로서 활용할 수 있을 뿐만 아니라, 신생돼지 췌도의 분리와 배양 및 정도 분석 기술을 개발함으로써, 당뇨병 치료 등 생명의학 분야에서 널리 활용될 수 있다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Korean (KO)
Filing Language: Korean (KO)