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1. (WO2018105803) COMPOSITION FOR SKIN WHITENING, ANTIOXIDATION, WRINKLE IMPROVEMENT, ANTIMICROBIAL ACTIVITY AND ANTI-INFLAMMATION COMPRISING UNRIPE APPLE EXTRACT AND BAICALIN AS ACTIVE INGREDIENTS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/105803 International Application No.: PCT/KR2016/015027
Publication Date: 14.06.2018 International Filing Date: 21.12.2016
IPC:
A61K 8/97 (2006.01) ,A61K 8/60 (2006.01) ,A61K 36/73 (2006.01) ,A61K 31/7048 (2006.01) ,A23L 33/105 (2016.01) ,A23L 33/10 (2016.01) ,A61Q 19/00 (2006.01) ,A61Q 17/00 (2006.01)
Applicants: THURINGEN KOREA CO., LTD.[KR/KR]; 52-10, Bonggi 1-gil, Punggak-myeon Cheongdo-gun Gyeongsangbuk-do 38307, KR
Inventors: KANG, Yeon Ja; KR
KIM, Jin Cheol; KR
PARK, Jong Kuk; KR
JEONG, Yong Ha; KR
JUN, Dong Ha; KR
CHEON, Jung Yoon; KR
PARK, Sang Mi; KR
JUNG, Da Woon; KR
HAN, Heyop Woo; KR
KIM, Myong Jun; KR
PARK, Dong Woo; KR
Agent: JEONG, Seong Jong; KR
SHIN, Myung Young; KR
Priority Data:
10-2016-016708008.12.2016KR
10-2016-016708108.12.2016KR
Title (EN) COMPOSITION FOR SKIN WHITENING, ANTIOXIDATION, WRINKLE IMPROVEMENT, ANTIMICROBIAL ACTIVITY AND ANTI-INFLAMMATION COMPRISING UNRIPE APPLE EXTRACT AND BAICALIN AS ACTIVE INGREDIENTS
(FR) COMPOSITION POUR LE BLANCHIMENT DE LA PEAU, L'ANTIOXYDATION, L'AMÉLIORATION DES RIDES, L'ACTIVITÉ ANTIMICROBIENNE ET L'ANTI-INFLAMMATION COMPRENANT UN EXTRAIT DE POMME PAS MÛRE ET DE LA BAÏCALINE À TITRE DE PRINCIPES ACTIFS
(KO) 미성숙 사과 추출물 및 바이칼린을 유효성분으로 포함하는 피부미백, 항산화, 주름개선, 항균 및 항염증을 위한 조성물
Abstract: front page image
(EN) The present invention relates to a composition containing a mixture of an unripe apple extract and baicalin. As the composition comprising a mixture of an unripe apple extract and baicalin as active ingredients of the present invention is excellent in inhibitory activity of tyrosinase, elastase, and collagenase, the composition is effective in skin whitening, antioxidation, and wrinkle improvement. Also, as the composition inhibits skin flora and has an excellent inhibitory effect on the expression of iNOS and NO, the composition has antimicrobial and anti-inflammatory effects. Moreover, the composition can be safely used in cosmetic compositions, pharmaceutical compositions and food compositions because the composition lacks cytotoxicity and skin side effects.
(FR) La présente invention concerne une composition contenant un mélange d'extrait de pomme pas mûre et de baïcaline. Comme la composition comprenant un mélange d'extrait de pomme pas mûre et de baïcaline à titre de principes actifs selon la présente invention a une excellente activité inhibitrice de la tyrosinase, de l'élastase et de la collagénase, elle est efficace pour le blanchiment de la peau, l'antioxydation et l'amélioration des rides. De plus, la composition inhibe la flore cutanée et a un excellent effet inhibiteur sur l'expression de iNOS et de NO, de sorte qu'elle a des effets antimicrobiens et anti-inflammatoires. L'absence de cytotoxicité et d'effets cutanés secondaires de la composition selon l'invention permet en outre de l'utiliser en toute sécurité dans les compositions cosmétiques, les compositions pharmaceutiques et les compositions alimentaires.
(KO) 본 발명은 미성숙 사과(unripe apple) 추출물 및 바이칼린의 혼합물을 함유하는 조성물에 관한 것으로, 본 발명의 미성숙 사과 추출물 및 바이칼린의 혼합물 유효성분으로 포함하는 조성물은 티로시나제, 엘라스타제 및 콜라겐아제 억제활성이 우수하여 피부미백, 항산화 및 주름개선에 효과가 있고, 피부상재균을 억제하고 iNOS 및 NO의 발현을 저해 효과가 우수하여 항균 및 항염증 효과가 있으며, 세포 독성 및 피부 부작용이 없어 화장료 조성물, 약학적 조성물 및 식품 조성물에 안전하게 사용할 수 있다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)