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1. (WO2018105738) ZINC CHLORIDE HYDROXIDE HAVING EXCELLENT ZINC ION SUSTAINED-RELEASABILITY AND PRODUCTION METHOD THEREFOR

Pub. No.:    WO/2018/105738    International Application No.:    PCT/JP2017/044220
Publication Date: Fri Jun 15 01:59:59 CEST 2018 International Filing Date: Sat Dec 09 00:59:59 CET 2017
IPC: A61K 33/30
A61L 15/18
A61P 17/02
Applicants: JFE MINERAL COMPANY, LTD.
JFEミネラル株式会社
Inventors: NAKATA Yoshimi
中田 圭美
ECHIZENYA Yuko
越前谷 木綿子
UDAGAWA Etsurou
宇田川 悦郎
YAMAMOTO Osamu
山本 修
Title: ZINC CHLORIDE HYDROXIDE HAVING EXCELLENT ZINC ION SUSTAINED-RELEASABILITY AND PRODUCTION METHOD THEREFOR
Abstract:
Provided are: zinc chloride hydroxide that is useful as a pharmaceutical ingredient, has excellent zinc ion sustained-releasability when used as a pharmaceutical agent, and exhibits excellent stability as a pharmaceutical ingredient; and a production method therefor. The present invention pertains to zinc chloride hydroxide that can be used as a pharmaceutical ingredient, that has excellent zinc ion sustained-releasability, that comprises at least one member selected from the group consisting of zinc chloride, zinc hydroxide, and zinc oxide, and that, after an elution test is performed on a zinc chloride hydroxide hydrate containing simonkolleite by an agitation method, shows a Zn2+ ion elution per surface area of 0.25-100 μg/m2 and a pH of not lower than 7.0 but lower than 8.3.