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1. (WO2018105681) OPHTHALMOLOGICAL COMPOSITION AND METHOD FOR PRODUCING SAME

Pub. No.:    WO/2018/105681    International Application No.:    PCT/JP2017/043924
Publication Date: Fri Jun 15 01:59:59 CEST 2018 International Filing Date: Fri Dec 08 00:59:59 CET 2017
IPC: A61K 31/01
A61K 9/107
A61K 47/06
A61K 47/44
A61P 27/02
A61P 27/04
Applicants: LION CORPORATION
ライオン株式会社
Inventors: YOSHIDA Masataka
吉田 雅貴
TAKAMURA Yumi
高村 裕美
Title: OPHTHALMOLOGICAL COMPOSITION AND METHOD FOR PRODUCING SAME
Abstract:
Provided is an ophthalmological composition which stabilizes the lacrimal lipid layer and has a clear external appearance. The ophthalmological composition contains (A) liquid paraffin and (B) a non-ionic surfactant, wherein the compounding mass ratio of (A) component, and (B-1) polyoxyethylene castor oil, (B-2) polyoxyethylene hydrogenated castor oil, and (B-3) a non-ionic surfactant other than (B-1) and (B-2) satisfy the expressions 0.5 ≤ ((B-1)+(B-2)+(B-3))/(A) and ((B-1)/0.75+(B-2)/2+(B-3)/0.05))/(A) ≤ 10.0.