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1. (WO2018104919) CHIMPANZEE ADENOVIRUS CONSTRUCTS WITH LYSSAVIRUS ANTIGENS

Pub. No.:    WO/2018/104919    International Application No.:    PCT/IB2017/057759
Publication Date: Fri Jun 15 01:59:59 CEST 2018 International Filing Date: Sat Dec 09 00:59:59 CET 2017
IPC: C07K 14/005
A61K 39/205
C12N 15/86
Applicants: GLAXOSMITHKLINE BIOLOGICALS SA
Inventors: AMMENDOLA, Virginia
COLLOCA, Stefano
VITELLI, Alessandra
WIZEL, Benjamin
Title: CHIMPANZEE ADENOVIRUS CONSTRUCTS WITH LYSSAVIRUS ANTIGENS
Abstract:
The invention provides adenoviral vectors comprising transgenes encoding Lyssaviral antigens. The vectors can be used to produce vaccines for the prophylaxis, amelioration and treatment of diseases caused by Lyssaviral diseases, e.g., rabies.