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1. (WO2018104874) ADJUVANT COMPOSITION COMPRISING A GROWTH FACTOR AND A NEUROPEPTIDE FOR ACCELERATING WOUND HEALING AND ORGAN RE-EPITHELISATION

Pub. No.:    WO/2018/104874    International Application No.:    PCT/IB2017/057673
Publication Date: Fri Jun 15 01:59:59 CEST 2018 International Filing Date: Thu Dec 07 00:59:59 CET 2017
IPC: A61K 38/18
A61P 17/02
Applicants: DESARROLLADORA Y COMERCIALIZADORA DE TECNOLOGÍAS BIOMÉDICAS DECOTECBIO S.A.S. DE C.V.
Inventors: RODRÍGUEZ ROJAS, Rafael
Title: ADJUVANT COMPOSITION COMPRISING A GROWTH FACTOR AND A NEUROPEPTIDE FOR ACCELERATING WOUND HEALING AND ORGAN RE-EPITHELISATION
Abstract:
The invention relates to the pharmaceutical and biotechnology industry for wound healing and organ re-epithelisation treatments. The advantages of the invention with respect to compositions of the prior art are that, in addition to accelerating the healing process, the composition makes it possible to speed up organ re-epithelisation without generating hyperplasia, thereby improving organ quality following a deterioration. The composition is formed by a growth factor and a neuropeptide. The growth factor is epidermal growth factor, while the neuropeptide is neurotensin. The composition contains epidermal growth factor in a concentration of 0.00001–10 mg/ml and neurotensin in a concentration of 0.00001–10 mg/ml. The combination can have any pharmaceutical form and can be administered by any route of administration.