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1. (WO2018104350) ULTRASONIC SONOTHROMBOLYSIS TREATMENT PLANNING

Pub. No.:    WO/2018/104350    International Application No.:    PCT/EP2017/081594
Publication Date: Fri Jun 15 01:59:59 CEST 2018 International Filing Date: Thu Dec 07 00:59:59 CET 2017
IPC: A61N 7/00
A61B 8/08
Applicants: KONINKLIJKE PHILIPS N.V.
Inventors: SUTTON, Jonathon Thomas
SEIP, Ralf
SHI, William Tao
POWERS, Jeffry Earl
Title: ULTRASONIC SONOTHROMBOLYSIS TREATMENT PLANNING
Abstract:
An ultrasound system utilizes an array transducer to perform sonothrombolysis treatment. The system also produces a vascular map of flow characteristics in the vicinity of the therapy site in a subject. The vascular map is used to formulate a treatment plan which includes the number, focusing, timing, and steering of beams of a pattern of therapy beams transmitted during a transmission interval. Formulation of the treatment plan considers factors such as the direction of microbubble flow toward a therapy site, the flow velocity, the spacing between successive therapy beam transmissions, the number of therapy beams needed to "paint" a therapy region, and grating lobe locations, many of which can be determined from the vascular map.