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1. (WO2018104305) FIELD OF APPLICATION OF THE INVENTION

Pub. No.:    WO/2018/104305    International Application No.:    PCT/EP2017/081530
Publication Date: Fri Jun 15 01:59:59 CEST 2018 International Filing Date: Wed Dec 06 00:59:59 CET 2017
IPC: C07C 311/46
A61K 31/18
A61P 29/00
C07D 205/04
C07D 207/06
C07D 207/10
C07D 207/12
C07D 209/94
C07D 209/96
C07D 211/38
C07D 213/75
C07D 275/06
C07D 295/13
C07D 295/192
C07D 307/14
C07D 307/77
C07D 309/04
C07D 405/12
C07D 491/10
Applicants: BAYER PHARMA AKTIENGESELLSCHAFT
Inventors: WERNER, Stefan
MESCH, Stefanie
OSMERS, Maren
NUBBEMEYER, Reinhard
Title: FIELD OF APPLICATION OF THE INVENTION
Abstract:
Substituted aromatic sulfonamides of formula (I) which are antagonists or negative allosteric modulators of P2X4, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease.