Search International and National Patent Collections

1. (WO2018104254) DEVICE AND METHOD FOR IDENTIFYING A REGION OF INTEREST (ROI)

Pub. No.:    WO/2018/104254    International Application No.:    PCT/EP2017/081425
Publication Date: Fri Jun 15 01:59:59 CEST 2018 International Filing Date: Wed Dec 06 00:59:59 CET 2017
IPC: G06K 9/00
G06K 9/32
Applicants: KONINKLIJKE PHILIPS N.V.
Inventors: ZUO, Fei
PIERIK, Anke
WIMBERGER-FRIEDL, Reinhold
DE LAAT, Koen
Title: DEVICE AND METHOD FOR IDENTIFYING A REGION OF INTEREST (ROI)
Abstract:
A device for identifying a region of interest to be dissected from a biological tissue sample is presented. The device comprises an image analyzing unit which iteratively grows the region of interest from an initial size to a final size as long as a target parameter which is based on the two detected densities D1 and D2 and which describes the region of interest, is above a predefined target value. Preferably, the target parameter is the density ratio D1/D2 of the region of interest and the first type of detected cells are tumor cells whereas the second type of cells are non-tumor cells. Furthermore, optimization or cost functions can be applied which take into account the percentage of number of cells of the first cell type and the total number of cells of the first cell type in the respective region of interest.