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1. (WO2018104228) MECHANOCHEMICAL SYNTHESIS OF RADIOGRAPHIC AGENTS INTERMEDIATES
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Pub. No.: WO/2018/104228 International Application No.: PCT/EP2017/081373
Publication Date: 14.06.2018 International Filing Date: 04.12.2017
IPC:
C07C 231/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
231
Preparation of carboxylic acid amides
Applicants:
BRACCO IMAGING SPA [IT/IT]; Via Egidio Folli, 50 20134 Milano, IT
Inventors:
BARGE, Alessandro; IT
BARICCO, Francesca; IT
CRAVOTTO, Giancarlo; IT
FRETTA, Roberta; IT
LATTUADA, Luciano; IT
Agent:
RAVIZZA, Claudio; IT
Priority Data:
16202152.105.12.2016EP
Title (EN) MECHANOCHEMICAL SYNTHESIS OF RADIOGRAPHIC AGENTS INTERMEDIATES
(FR) SYNTHÈSE MÉCANOCHIMIQUE D'INTERMÉDIAIRES D'AGENTS RADIOGRAPHIQUES
Abstract:
(EN) The present invention generally relates to a process using a mechanochemical approach exploiting the mechanical milling of reactants for the manufacturing of acetyl Iopamidol and, more generally, of key intermediates of radiographic contrast agents, and of the contrast agents themselves.
(FR) La présente invention concerne de manière générale un procédé utilisant une approche mécanochimique exploitant le broyage mécanique de réactifs pour la fabrication d'acétyl iopamidol et plus généralement, d'intermédiaires clés d'agents de contraste radiographique, et les agents de contraste à proprement dit.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)