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|1. (WO2018103759) SELF-ASSEMBLED DRUG-LOADING SYSTEM AND PREPARATION METHOD THEREFOR|
|Applicants:||JIANGXI KEWEI COLLABORATIVE INNOVATION PHARMACEUTICAL CO., LTD.
|Title:||SELF-ASSEMBLED DRUG-LOADING SYSTEM AND PREPARATION METHOD THEREFOR|
Disclosed are a self-assembled drug-loading system containing a hydrophilic phototherapeutic drug and a hydrophobic chemotherapeutic drug, a preparation method therefor and the use thereof for preparing an anti-tumour drug. The self-assembled drug-loading system is a water-soluble complex or water-dispersible nanoparticles formed by means ofπ-π interaction or hydrophobic interaction between the phototherapeutic drug and the chemotherapeutic drug, wherein the molar ratio of the phototherapeutic drug to the chemotherapeutic drug is 2 : 1 to 1 : 10.