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1. (WO2018103757) BIPHENYL COMPOUND AS CCR2/CCR5 RECEPTOR ANTAGONIST

Pub. No.:    WO/2018/103757    International Application No.:    PCT/CN2017/115453
Publication Date: Fri Jun 15 01:59:59 CEST 2018 International Filing Date: Tue Dec 12 00:59:59 CET 2017
IPC: C07D 213/06
C07D 233/54
C07D 249/08
A61K 31/4164
A61K 31/4196
A61K 31/4409
A61P 29/00
Applicants: GUANGDONG ZHONGSHENG PHARMACEUTICAL CO., LTD
广东众生药业股份有限公司
MEDSHINE DISCOVERY INC.
南京明德新药研发股份有限公司
Inventors: LUO, Yunfu
罗云富
LONG, Chaofeng
龙超峰
BA, Yuyong
巴庾勇
CHEN, Xiaoxin
陈小新
CHEN, Shuhui
陈曙辉
Title: BIPHENYL COMPOUND AS CCR2/CCR5 RECEPTOR ANTAGONIST
Abstract:
Provided is a CCR2/CCR5 receptor antagonist and the use thereof in the preparation of a drug for treating diseases associated with the CCR2/CCR5. In particular, disclosed are a compound represented by formula (I) and a pharmaceutically acceptable salt thereof.