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1. (WO2018103739) ANTIBODY-DRUG CONJUGATE, PREPARATION METHOD, INTERMEDIATE, PHARMACEUTICAL COMPOSITION AND USE
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/103739 International Application No.: PCT/CN2017/115281
Publication Date: 14.06.2018 International Filing Date: 08.12.2017
IPC:
A61K 47/68 (2017.01) ,A61K 31/704 (2006.01) ,A61P 35/00 (2006.01)
Applicants: XDCEXPLORER (SHANGHAI) CO., LTD.[CN/CN]; Room 302, No. 3 Building, Lane 720 Cailun Road, Zhangjiang High-Tech Park, Pudong New Area Shanghai 201203, CN
Inventors: XIANG, Jason Shaoyun; CN
MA, Xingquan; CN
YANG, Hongyu; CN
XIE, Tiegang; CN
Agent: SHANGHAI BESHINING LAW OFFICE; 21st Floor SFECO Mansion 681 Xiaomuqiao Road Shanghai 200032, CN
Priority Data:
201611129379.109.12.2016CN
Title (EN) ANTIBODY-DRUG CONJUGATE, PREPARATION METHOD, INTERMEDIATE, PHARMACEUTICAL COMPOSITION AND USE
(FR) CONJUGUÉ ANTICORPS-MÉDICAMENT, PROCÉDÉ DE PRÉPARATION, INTERMÉDIAIRE, COMPOSITION PHARMACEUTIQUE ET UTILISATION
(ZH) 抗体药物偶联物、制备方法、中间体、药物组合物及应用
Abstract:
(EN) Provided are an antibody-drug conjugate, a preparation method, an intermediate, a pharmaceutical composition and the use thereof. The antibody-drug conjugate has high cytotoxicity and good anti-cancer effects, and has a market application prospect.
(FR) L'invention concerne un conjugué anticorps-médicament, un procédé de préparation, un intermédiaire, une composition pharmaceutique et l'utilisation de celui-ci. Le conjugué anticorps-médicament a une cytotoxicité élevée et de bons effets anticancéreux, et a une perspective d'application de marché.
(ZH) 提供一种抗体药物偶联物、制备方法、中间体、药物组合物及其应用,该抗体药物偶联物细胞毒性高,抗癌效果好,具有市场应用前景。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)