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|1. (WO2018103654) ARTIFICIAL OVARY AND PREPARATION AND APPLICATION OF SAME|
|Applicants:||SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY
|Title:||ARTIFICIAL OVARY AND PREPARATION AND APPLICATION OF SAME|
An artificial ovary and a preparation and application of the same. The artificial ovary comprises a biocompatible frame, follicular cells, and a coating mixed liquid, wherein the coating mixed liquid covers the outside of the follicular cells, enters inside voids of the biocompatible frame, and is made from a coated excipient and a biological hormone, and the biocompatible frame is fabricated by 3D printing. The artificial ovary is suitable for composing a research tool for cellular studies of the whole or part of primordial follicles, preantral follicles, and luminal follicles of any species, and is also suitable for a screening model for a factor, a prodrug, and the like related to primordial follicles, preantral follicles, and luminal follicles, and for a prevention or treatment tool for a disease directly or indirectly related to ovarian damage caused by any factor.