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1. (WO2018103624) USE OF κ OPIOID RECEPTOR AGONIST IN PREPARATION OF DRUG FOR TREATING PRURITUS CAUSED BY FARNESOL X RECEPTOR AGONIST

Pub. No.:    WO/2018/103624    International Application No.:    PCT/CN2017/114571
Publication Date: Fri Jun 15 01:59:59 CEST 2018 International Filing Date: Wed Dec 06 00:59:59 CET 2017
IPC: A61K 45/06
A61K 31/575
A61K 31/485
A61K 38/07
A61P 17/04
A61P 9/12
A61P 1/16
Applicants: JIANGSU HENGRUI MEDICINE CO., LTD.
江苏恒瑞医药股份有限公司
Inventors: SUN, Piaoyang
孙飘扬
GUI, Yuzhou
桂雨舟
YANG, Changyong
杨昌永
ZHANG, Lianshan
张连山
HUANG, Xiaoxing
黄晓星
Title: USE OF κ OPIOID RECEPTOR AGONIST IN PREPARATION OF DRUG FOR TREATING PRURITUS CAUSED BY FARNESOL X RECEPTOR AGONIST
Abstract:
The present invention relates to the use of a κ opioid receptor agonist in the preparation of a drug for treating pruritus caused by a farnesol X receptor agonist. The present invention also relates to the use of a farnesol X receptor agonist in combination with a κ opioid receptor agonist in the preparation of a drug for treating portal hypertension, cholestatic liver disease, primary biliary cirrhosis, bile acid diarrhoea or non-alcoholic fatty liver.