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1. (WO2018103060) INHIBITORS OF BRUTON'S TYROSINE KINASE AND METHODS OF THEIR USE

Pub. No.:    WO/2018/103060    International Application No.:    PCT/CN2016/109143
Publication Date: Fri Jun 15 01:59:59 CEST 2018 International Filing Date: Sat Dec 10 00:59:59 CET 2016
IPC: C07D 495/16
C07D 519/00
A61K 31/519
A61P 35/00
A61P 37/00
A61P 19/00
Applicants: JANSSEN PHARMACEUTICA NV
CAI, Min
Inventors: CAI, Min
ARORA, Nidhi
BACANI, Genesis M.
BARBAY, Joseph Kent
BEMBENEK, Scott D.
CHEN, Wei
DECKHUT, Charlotte Pooley
EDWARDS, James P.
GHOSH, Brahmananda
KREUTTER, Kevin D.
LI, Gang
TICHENOR, Mark S.
VENABLE, Jennifer D.
WEI, Jianmei
WIENER, John J. M.
WU, Yao
XIAO, Kun
ZHANG, Feihuang
ZHU, Yaoping
Title: INHIBITORS OF BRUTON'S TYROSINE KINASE AND METHODS OF THEIR USE
Abstract:
The present disclosure is directed to compounds of Formula (I) and methods of their use and preparation, as well as compositions comprising compounds of Formula (I).