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1. (WO2018102914) USE OF MEDIUM-CHAIN TRIGLYCERIDES FOR THE MANAGEMENT OF METABOLIC CONDITIONS
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Pub. No.: WO/2018/102914 International Application No.: PCT/CA2017/051463
Publication Date: 14.06.2018 International Filing Date: 05.12.2017
IPC:
A61K 31/23 (2006.01) ,A61P 3/00 (2006.01) ,A61P 3/08 (2006.01) ,C07C 69/30 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
21
Esters, e.g. nitroglycerine, selenocyanates
215
of carboxylic acids
22
of acyclic acids, e.g. pravastatin
23
of acids having a carboxyl group bound to a chain of seven or more carbon atoms
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3
Drugs for disorders of the metabolism
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3
Drugs for disorders of the metabolism
08
for glucose homeostasis
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
69
Esters of carboxylic acids; Esters of carbonic or haloformic acids
02
Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
22
having three or more carbon atoms in the acid moiety
30
esterified with trihydroxylic compounds
Applicants:
TRANSFERT PLUS, SOCIÉTÉ EN COMMANDITE [CA/CA]; 355 Peel Street, Carrefour INGO, Suite 503 Montréal, Québec H3C 2G9, CA
Inventors:
MOUNIER, Catherine; CA
RIAL, Sabri; CA
Agent:
LAVERY, DE BILLY, LLP; 1 Place Ville Marie, Suite 4000 Montréal, Québec H3B 4M4, CA
Priority Data:
62/430,59306.12.2016US
Title (EN) USE OF MEDIUM-CHAIN TRIGLYCERIDES FOR THE MANAGEMENT OF METABOLIC CONDITIONS
(FR) UTILISATION DE TRIGLYCÉRIDES À CHAÎNE MOYENNE POUR LA GESTION DE TROUBLES DU MÉTABOLISME
Abstract:
(EN) The use of a composition comprising an effective amount of medium-chain triglycerides (MCT) or medium-chain fatty acids (MCFA), such as caprylic acids and/or capric acids, for preventing or reducing a metabolic condition selected from insulin resistance, glucose intolerance, non-alcoholic fatty liver disease (NAFLD) or non-alcoholic steatohepatitis (NASH) in a subject, is disclosed. The composition may be in the form of a food composition or food supplement, or a pharmaceutical composition.
(FR) L'invention concerne l'utilisation d'une composition comprenant une quantité efficace de triglycérides à chaîne moyenne (TCM) ou d'acides gras à chaîne moyenne (AGCM), tels que les acides capryliques et/ou les acides capriques, pour prévenir ou faire diminuer chez le patient un trouble métabolique appartenant au groupe comprenant la résistance à l'insuline, l'intolérance au glucose, la stéatose hépatique non alcoolique (NAFLD) et la stéatohépatite non alcoolique (NASH). La composition peut se présenter sous la forme d'une composition alimentaire ou d'un complément alimentaire, ou d'une composition pharmaceutique.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)