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1. (WO2018102812) DEVICES AND METHODS FOR NERVE REGENERATION

Pub. No.:    WO/2018/102812    International Application No.:    PCT/US2017/064499
Publication Date: Fri Jun 08 01:59:59 CEST 2018 International Filing Date: Tue Dec 05 00:59:59 CET 2017
IPC: A61B 17/11
A61B 17/00
A61B 17/04
A61L 27/26
Applicants: INTEGRA LIFESCIENCES CORPORATION
Inventors: ARCHIBALD, Simon J.
O'BRIEN, Fergal
MATSIKO, Amos
Title: DEVICES AND METHODS FOR NERVE REGENERATION
Abstract:
The present invention is directed to a nerve regeneration conduit including a resorbable tube having a matrix therein. The matrix is characterized by substantially parallel, axially aligned pores extending the length of the matrix. The matrix is formed by the axial freezing of a slurry having little or no significant radial thermal gradient during the freezing process. The matrix is used to bridge the gap between the severed ends of a nerve and provide a scaffold for nerve regeneration.