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1. (WO2018102760) METHODS OF INDUCING IMMUNE TOLERANCE TO CLOTTING FACTORS

Pub. No.:    WO/2018/102760    International Application No.:    PCT/US2017/064323
Publication Date: Fri Jun 08 01:59:59 CEST 2018 International Filing Date: Sat Dec 02 00:59:59 CET 2017
IPC: A61K 38/37
A61K 38/48
A61P 7/04
Applicants: BIOVERATIV THERAPEUTICS INC.
SWEDISH ORPHAN BIOVITRUM AB (PUBL)
Inventors: DUMONT, Jennifer
JAIN, Nisha
LETHAGEN, Stefan
Title: METHODS OF INDUCING IMMUNE TOLERANCE TO CLOTTING FACTORS
Abstract:
The present disclosure provides methods inducing immune tolerance in a human, comprising administering to the human an effective amount of a composition or a chimeric protein comprising a clotting factor and an Fc region.