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1. (WO2018102750) PULP REGENERATION COMPOSITIONS AND METHODS OF FORMING AND USING THE SAME
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Pub. No.: WO/2018/102750 International Application No.: PCT/US2017/064312
Publication Date: 07.06.2018 International Filing Date: 01.12.2017
IPC:
A61K 35/32 (2015.01) ,A61K 35/51 (2015.01) ,A61L 27/38 (2006.01) ,A61L 27/52 (2006.01)
[IPC code unknown for A61K 35/32][IPC code unknown for A61K 35/51][IPC code unknown for A61L 27/38][IPC code unknown for A61L 27/52]
Applicants:
TRUSTEES OF TUFTS COLLEGE [US/US]; Ballou Hall 1 The Green Medford, Massachusetts 02155, US
THE BRIGHAM AND WOMEN'S HOSPITAL, INC. [US/US]; 215 First Street, Suite 500 Cambridge, Massachusetts 02142, US
Inventors:
YELICK, Pamela, C.; US
KHADEMHOSSEINI, Ali; US
Agent:
RESNICK, David, S.; US
BAIO, Elizabeth, W.; US
BURNHAM, Daniel, J.; US
CIMPOES, Sorinel; US
Priority Data:
62/428,87001.12.2016US
Title (EN) PULP REGENERATION COMPOSITIONS AND METHODS OF FORMING AND USING THE SAME
(FR) COMPOSITIONS DE RÉGÉNÉRATION DE PULPE ET PROCÉDÉS DE FORMATION ET D'UTILISATION DE CELLES-CI
Abstract:
(EN) A dental tissue regenerative composition. The composition includes a combination of (1) human dental pulp stem cells and (2) at least one of human umbilical vein endothelial cells or vascular endothelial growth factor. The combination is encapsulated in a light-activated gelatin methacrylate hydrogel.
(FR) L'invention concerne une composition de régénération de tissu dentaire. La composition comprend une combinaison de (1) cellules souches de pulpe dentaire humaine et (2) d'au moins des cellules endothéliales de veine ombilicale humaine et/ou du facteur de croissance endothéliale vasculaire. La combinaison est encapsulée dans un hydrogel de méthacrylate de gélatine activé par la lumière.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)