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1. (WO2018102740) COMPOSITIONS AND METHODS RELATED TO CELL SYSTEMS FOR PENETRATING SOLID TUMORS

Pub. No.:    WO/2018/102740    International Application No.:    PCT/US2017/064299
Publication Date: Fri Jun 08 01:59:59 CEST 2018 International Filing Date: Sat Dec 02 00:59:59 CET 2017
IPC: A61K 35/18
A61P 35/00
Applicants: RUBIUS THERAPEUTICS, INC.
Inventors: KAHVEJIAN, Avak
DEANS, Robert, J.
MATA-FINK, Jordi
ELLOUL, Sivan
DOWDEN, Nathan
Title: COMPOSITIONS AND METHODS RELATED TO CELL SYSTEMS FOR PENETRATING SOLID TUMORS
Abstract:
The present disclosure provides, e.g., compositions and method for treating cancers, e.g., solid tumors. In embodiments, the compositions comprise an erythroid cell expressing an exogenous polypeptide, e.g., a polypeptide that promotes penetration of the erythroid cell into the solid tumor.