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1. (WO2018102740) COMPOSITIONS AND METHODS RELATED TO CELL SYSTEMS FOR PENETRATING SOLID TUMORS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/102740    International Application No.:    PCT/US2017/064299
Publication Date: 07.06.2018 International Filing Date: 01.12.2017
IPC:
A61K 35/18 (2015.01), A61P 35/00 (2006.01)
Applicants: RUBIUS THERAPEUTICS, INC. [US/US]; 325 Vassar St Suite 1A Cambridge, MA 02139 (US).
DEANS, Robert, J. [US/US]; (US).
ELLOUL, Sivan [US/US]; (US).
DOWDEN, Nathan [US/US]; (US)
Inventors: DEANS, Robert, J.; (US).
ELLOUL, Sivan; (US).
DOWDEN, Nathan; (US).
KAHVEJIAN, Avak; (US).
MATA-FINK, Jordi; (US)
Agent: KOYFMAN, Hannah, R.; (US)
Priority Data:
62/429,275 02.12.2016 US
Title (EN) COMPOSITIONS AND METHODS RELATED TO CELL SYSTEMS FOR PENETRATING SOLID TUMORS
(FR) COMPOSITIONS ET MÉTHODES SE RAPPORTANT À DES SYSTÈMES CELLULAIRES DESTINÉS À PÉNÉTRER DANS DES TUMEURS SOLIDES
Abstract: front page image
(EN)The present disclosure provides, e.g., compositions and method for treating cancers, e.g., solid tumors. In embodiments, the compositions comprise an erythroid cell expressing an exogenous polypeptide, e.g., a polypeptide that promotes penetration of the erythroid cell into the solid tumor.
(FR)La présente invention concerne, par exemple, des compositions et une méthode pour traiter des cancers, par exemple, des tumeurs solides. Dans des modes de réalisation, les compositions comprennent une cellule érythroïde exprimant un polypeptide exogène, par exemple, un polypeptide qui favorise la pénétration de la cellule érythroïde dans la tumeur solide.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)