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1. (WO2018102675) NOVEL USES OF PCSK9 INHIBITORS AND RELATED MEDICATIONS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/102675    International Application No.:    PCT/US2017/064203
Publication Date: 07.06.2018 International Filing Date: 01.12.2017
IPC:
A61K 31/4745 (2006.01), A61K 38/17 (2006.01), A61K 39/395 (2006.01), A61P 1/16 (2006.01), A61P 29/00 (2006.01)
Applicants: BHL PATENT HOLDINGS, LLC [US/US]; 8 State Street Towanda, PA 18848 (US) (For All Designated States Except US)
Inventors: LEVIN, Bruce, H.; (US)
Agent: FEIN, Michael, B.; (US)
Priority Data:
62/428,641 01.12.2016 US
Title (EN) NOVEL USES OF PCSK9 INHIBITORS AND RELATED MEDICATIONS
(FR) NOUVELLES UTILISATIONS D'INHIBITEURS DE PCSK9 ET MÉDICAMENTS ASSOCIÉS
Abstract: front page image
(EN)A method comprising administering an agent, for example a PCSK9 inhibitor, to a patient who suffers from fatty liver disease or is at risk of fatty liver disease, thereby reducing the risk of fatty liver disease, severity of fatty liver disease, symptoms of such disease, or signs of such disease and a method comprising administering a PCSK9 inhibitor to a patient having symptoms of elevated liver enzymes to ameliorate said symptoms.
(FR)La présente invention porte sur un procédé consistant à administrer un agent, par exemple un inhibiteur de PCSK9, à un patient qui souffre d'une maladie du foie gras ou présente un risque de maladie du foie gras, ce qui permet de réduire le risque de maladie du foie gras, la sévérité d'une telle maladie, les symptômes d'une telle maladie, ou des signes d'une telle maladie, et sur un procédé consistant à administrer un inhibiteur de PCSK9 à un patient présentant des symptômes d'enzymes hépatiques élevées pour améliorer lesdits symptômes.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)