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1. (WO2018102660) IN SITU PROBE INVERSION PROCESS FOR CONSTRUCTING PROBE ARRAYS

Pub. No.:    WO/2018/102660    International Application No.:    PCT/US2017/064169
Publication Date: Fri Jun 08 01:59:59 CEST 2018 International Filing Date: Sat Dec 02 00:59:59 CET 2017
IPC: B05D 3/10
C07H 21/04
C12Q 1/68
Applicants: CENTRILLION TECHNOLOGIES, INC.
ZHOU, Wei
Inventors: ZHOU, Wei
SINGH, Vijay
Title: IN SITU PROBE INVERSION PROCESS FOR CONSTRUCTING PROBE ARRAYS
Abstract:
The present disclosure relates to processes for inverting oligonucleotide probes in an in situ synthesized array. These processes can be used to reverse the orientation of probes with respect to the substrate from 3, -bound to 5, -bound. These processes can also be used to reduce or eliminate the presence of truncated probe sequences from an in situ synthesized array.