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1. (WO2018102657) DNA ANTIBODY CONSTRUCTS FOR USE AGAINST EBOLA VIRUS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/102657    International Application No.:    PCT/US2017/064161
Publication Date: 07.06.2018 International Filing Date: 01.12.2017
IPC:
A61K 35/76 (2015.01), A61K 39/12 (2006.01), A61K 39/395 (2006.01), A61K 39/42 (2006.01), C07K 14/005 (2006.01), C07K 14/08 (2006.01), C07K 16/10 (2006.01), C12N 15/63 (2006.01), C12N 7/04 (2006.01), C12N 5/10 (2006.01)
Applicants: WEINER, David, B. [US/US]; (US).
PATEL, Ami [US/US]; (US)
Inventors: WEINER, David, B.; (US).
PATEL, Ami; (US)
Agent: SLAUGHTER, Alison; (US).
ALLEN, Justin; (US).
ARTIS, Ryan; (US).
CHEN, Ming; (US).
CAMPBELL, Christopher; (US)
Priority Data:
62/429,454 02.12.2016 US
62/559,422 15.09.2017 US
62/504,436 10.05.2017 US
Title (EN) DNA ANTIBODY CONSTRUCTS FOR USE AGAINST EBOLA VIRUS
(FR) CONSTRUCTIONS D'ANTICORPS ANTI-ADN POUR UNE UTILISATION CONTRE LE VIRUS EBOLA
Abstract: front page image
(EN)Disclosed herein is a composition including a recombinant nucleic acid sequence that encodes an antibody to an Ebola viral antigen. Also disclosed herein is a method of generating a synthetic antibody in a subject by administering the composition to the subject. The disclosure also provides a method of preventing and/or treating an Ebola virus infection in a subject using said composition and method of generation.
(FR)La présente invention concerne une composition comportant une séquence d'acides nucléiques de recombinaison qui code pour un anticorps contre un antigène du virus Ebola. L'invention concerne également un procédé de production d'un anticorps synthétique chez un sujet par administration de la composition au sujet. L'invention concerne également une méthode de prévention et/ou de traitement d’une infection par le virus Ebola chez un sujet au moyen de ladite composition et dudit procédé de production.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)