Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2018102537) METHODS AND KITS FOR CANCER ANTIGEN AND HEPARAN SULFATE IMAGING
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/102537 International Application No.: PCT/US2017/063920
Publication Date: 07.06.2018 International Filing Date: 30.11.2017
IPC:
A61K 38/45 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
43
Enzymes; Proenzymes; Derivatives thereof
45
Transferases (2)
Applicants:
BIO-TECHNE CORPORATION [US/US]; 614 McKinley Place NE Minneapolis, Minnesota 55413, US
Inventors:
WU, Zhengliang L.; US
PERSON, Anthony D.; US
Agent:
RAHLIN, Katherine J.; US
BUSS, Eric D.; US
FAIRBAIRN, Kara K.; US
GANESAN, Krithiga; US
GINZBURG, Michael; US
HIPKINS, Thomas R.; US
KADIEVITCH, Natalie D.; US
LAVANWAY, JR., Paul J.; US
PARZYCH, John S.; US
SEGELBAUM, Charles D.; US
SNUSTAD, Eric J.; US
SPANHEIMER, Ryan M.; US
WEST, David C.; US
ENG, Malissa C.; US
Priority Data:
62/428,21630.11.2016US
Title (EN) METHODS AND KITS FOR CANCER ANTIGEN AND HEPARAN SULFATE IMAGING
(FR) PROCÉDÉS ET KITS POUR L’IMAGERIE D’ANTIGÈNE DE CANCER ET DE SULFATE D’HÉPARANE
Abstract:
(EN) An in vitro method of imaging a cancer antigen includes providing a cell sample including a cancer antigen selected from the group consisting of a Tn antigen, a T antigen, a sialylated-Tn antigen, and a sialylated-T antigen, treating the sample with a glycosyltransferase to incorporate a carbohydrate with a click chemistry moiety into the cancer antigen, adding a label to the sample that includes a click chemistry moiety that reacts to the click chemistry moiety of the carbohydrate such that the label attaches to the carbohydrate to form a labeled cancer antigen, and imaging the sample with a camera.
(FR) La présente invention concerne un procédé in vitro d’imagerie d’un antigène de cancer qui comprend la fourniture d’un échantillon de cellules comprenant un antigène de cancer choisi dans le groupe constitué d’un antigène Tn, un antigène T, un antigène Tn sialylé et un antigène T sialylé, le traitement de l’échantillon avec une glycosyltransférase pour incorporer un glucide avec un fragment de chimie click dans l’antigène de cancer, l’ajout d’un marqueur à l’échantillon qui comprend un fragment de chimie click qui réagit avec le fragment de chimie click du glucide de sorte que le marqueur se lie au glucide pour former un antigène de cancer marqué, et l’imagerie de l’échantillon avec une caméra.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)