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1. (WO2018102506) TYROSINE DERIVATIVES AND COMPOSITIONS COMPRISING THEM
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/102506 International Application No.: PCT/US2017/063865
Publication Date: 07.06.2018 International Filing Date: 30.11.2017
IPC:
A61K 45/06 (2006.01) ,A61K 31/195 (2006.01) ,A61P 35/00 (2006.01)
Applicants: TYME, INC.[US/US]; 2711 Centerville Road Suite 400 Wilmington, DE 19808, US
Inventors: HOFFMAN, Steven; US
Agent: LUCCI, Joseph; US
DOYLE, Timothy, J.; US
Priority Data:
15/365,12030.11.2016US
Title (EN) TYROSINE DERIVATIVES AND COMPOSITIONS COMPRISING THEM
(FR) DÉRIVÉS DE TYROSINE ET COMPOSITIONS LES COMPRENANT
Abstract:
(EN) Compositions and kits comprising a tyrosine hydroxylase inhibitor and an anticancer agent that is chemically bonded to, or physically associated with, the tyrosine hydroxylase inhibitor are provided. Also provided are methods for reducing cell proliferation in a subject comprising administering to a subject in need thereof a composition comprising a tyrosine hydroxylase inhibitor and an anticancer agent that is chemically bonded to, or physically associated with, the tyrosine hydroxylase inhibitor.
(FR) L'invention concerne des compositions et des kits comprenant un inhibiteur de la tyrosine hydroxylase et un agent anticancéreux qui est chimiquement lié à, ou physiquement associé à, l'inhibiteur de la tyrosine hydroxylase. L'invention concerne également des procédés de réduction de la prolifération cellulaire chez un sujet comprenant l'administration à un sujet qui en a besoin d'une composition comprenant un inhibiteur de la tyrosine hydroxylase et un agent anticancéreux qui est lié chimiquement à, ou physiquement associé à, l'inhibiteur de la tyrosine hydroxylase.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)