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1. (WO2018102480) METHODS OF FABRICATING HYPER COMPLIANT POLYMER PARTICLES AND METHODS OF USE AND COMPOSITIONS
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Pub. No.: WO/2018/102480 International Application No.: PCT/US2017/063825
Publication Date: 07.06.2018 International Filing Date: 30.11.2017
IPC:
C08F 2/04 (2006.01) ,C08F 2/06 (2006.01) ,C08F 2/08 (2006.01) ,C08F 2/22 (2006.01) ,C08F 2/32 (2006.01) ,A61K 9/16 (2006.01)
C CHEMISTRY; METALLURGY
08
ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
F
MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
2
Processes of polymerisation
04
Polymerisation in solution
C CHEMISTRY; METALLURGY
08
ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
F
MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
2
Processes of polymerisation
04
Polymerisation in solution
06
Organic solvent
C CHEMISTRY; METALLURGY
08
ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
F
MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
2
Processes of polymerisation
04
Polymerisation in solution
06
Organic solvent
08
with the aid of dispersing agents for the polymer
C CHEMISTRY; METALLURGY
08
ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
F
MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
2
Processes of polymerisation
12
Polymerisation in non-solvents
16
Aqueous medium
22
Emulsion polymerisation
C CHEMISTRY; METALLURGY
08
ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
F
MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
2
Processes of polymerisation
32
Polymerisation in water-in-oil emulsions
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
14
Particulate form, e.g. powders
16
Agglomerates; Granulates; Microbeadlets
Applicants:
BROWN UNIVERSITY [US/US]; 350 Eddy Street, 5th Floor Providence, Rhode Island 02903, US
Inventors:
DARLING, Eric M.; US
LABRIOLA, Nicholas R.; US
MATHIOWITZ, Edith; US
Agent:
GUTERMAN, Sonia K.; US
Priority Data:
62/428,02930.11.2016US
62/520,06615.06.2017US
Title (EN) METHODS OF FABRICATING HYPER COMPLIANT POLYMER PARTICLES AND METHODS OF USE AND COMPOSITIONS
(FR) PROCÉDÉS DE FABRICATION DE PARTICULES POLYMÈRES HYPER-CONFORMABLES, ET PROCÉDÉS D'UTILISATION ET COMPOSITIONS
Abstract:
(EN) Compositions and methods are provided for making hyper compliant polymer particles by inverse emulsification and having a predetermined mechanical compliance and a predetermined size with a monodisperse diameter. Compositions and methods are provided for use of hyper compliant polymer particles in drug delivery, assay, particle image velocimetry, ceramics, cosmetics, deconvolution, electronic paper, insulation, personal care, standards, retroreflective paint and paint applications, thickening agents, regenerative medicine, device calibration, micro-carriers and force indicators.
(FR) L'invention concerne des compositions et des procédés destinés à fabriquer des particules polymères hyper-conformables par émulsification inverse, et présentant une conformabilité mécanique prédéterminée et une grosseur prédéterminée, avec un diamètre monodispersé. L'invention concerne des compositions et des procédés destinés à l'utilisation de particules polymères hyper-conformables pour l'administration des médicaments, les essais, la vélocimétrie par image de particules, les céramiques, les cosmétiques, la déconvolution, le papier électronique, l'isolation, les soins personnels, les normes, les peintures et applications des peintures rétroréfléchissantes, les agents épaississants, la médecine régénérative, l'étalonnage des dispositifs, les micro-supports et les dynamomètres.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)