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1. (WO2018102307) MICRONEEDLE FABRICATION AND DEVICE IMPLANTATION

Pub. No.:    WO/2018/102307    International Application No.:    PCT/US2017/063492
Publication Date: Fri Jun 08 01:59:59 CEST 2018 International Filing Date: Wed Nov 29 00:59:59 CET 2017
IPC: A61B 17/00
Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventors: HANSON, Timothy L.
SABES, Philip N.
Title: MICRONEEDLE FABRICATION AND DEVICE IMPLANTATION
Abstract:
Methods are provided for the fabrication of microneedles. Microneedles fabricated according to the herein described methods will generally be constructed of multiple lengths of wire winded together, brazed and further manipulated to include a reversible engagement feature. The subject microneedles may find use in a variety of applications and, among other purposes, the reversible engagement feature of such a microneedle may by employed in implanting an implantable device into a biological tissue. Also provided are methods of inserting an implantable device into a biological tissue having an outer membrane. The subject methods may include ablating a section of the outer membrane and inserting the implantable device through the ablated section of outer membrane, including e.g., where the implantable device is inserted using a microneedle including e.g., those microneedles for which methods of fabrication are provided herein.