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1. (WO2018102262) INHIBITORS OF PROTEIN ARGININE DEIMINASES (PADS) AND METHODS OF PREPARATION AND USE THEREOF

Pub. No.:    WO/2018/102262    International Application No.:    PCT/US2017/063324
Publication Date: Fri Jun 08 01:59:59 CEST 2018 International Filing Date: Tue Nov 28 00:59:59 CET 2017
IPC: A61K 38/06
A61K 31/205
C07C 257/14
Applicants: UNIVERSITY OF MASSACHUSETTS
Inventors: THOMPSON, Paul, R.
MUTH, Aaron
SUBRAMANIAN, Venkataraman
Title: INHIBITORS OF PROTEIN ARGININE DEIMINASES (PADS) AND METHODS OF PREPARATION AND USE THEREOF
Abstract:
The invention provides novel inhibitors or inactivators of protein arginine deiminases, pharmaceutical compositions and methods of use thereof. The invention also relates to molecular probes based on such compounds and methods of use thereof.