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1. (WO2018102171) SPECTRAL IMAGING SYSTEMS AND METHODS OF GENERATING SPECTRAL IMAGE DATA USING THE SAME
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CLAIMS

What is claimed is:

1. A spectral imaging system comprising:

a focal plane array, wherein:

the focal plane array comprises a plurality of imaging pixel rows; each imaging pixel row of the plurality of imaging pixel rows comprises two or more individual imaging pixels; and

the plurality of imaging pixel rows comprise a first imaging pixel row and a second imaging pixel row;

a reference filter optically coupled to the first imaging pixel row of the focal plane array; and

a multivariate optical element optically coupled to the second imaging pixel row of the focal plane array.

2. The spectral imaging system of claim 1, further comprising imaging optics comprising at least one lens optically coupled to the focal plane array, wherein the focal plane array and the imaging optics are positioned relative each other such that a focal point of the at least one lens is incident on the focal plane array.

3. The spectral imaging system of claim 1 or 2, further comprising an imaging controller comprising one or more processors and one or more memory modules, wherein:

the imaging controller is communicatively coupled to the focal plane array and configured to process signals output by the focal plane array and generate image data based signals output by a subset of the plurality of imaging pixel rows of the focal plane array; and the subset of the plurality of imaging pixel rows includes the first pixel row and the second pixel row.

4. The spectral imaging system of claim 3, wherein:

the plurality of imaging pixel rows comprise an unfiltered imaging pixel row that is not optically coupled to the multivariate optical element or the reference filter; and

the subset of the plurality of imaging pixel rows does not include the unfiltered imaging pixel row.

5. The spectral imaging system of any of claims 1-4, wherein the multivariate optical element is configured to permit traversal of light comprising one or more wavelengths of a spectral signature through the multivariate optical element and prevent traversal of light comprising one or more wavelengths outside of the spectral signature through the multivariate optical element.

6. The spectral imaging system of any of claims 1-5, wherein the multivariate optical element comprises a first multivariate optical element and the spectral imaging system further comprises a second multivariate optical element optically coupled to a third imaging pixel row of the plurality of imaging pixel rows, wherein the second imaging pixel row is positioned between the first imaging pixel row and the third imaging pixel row.

7. The spectral imaging system of any of claims 1-6, wherein the reference filter comprises a neutral density filter configured to reduce the intensity of light received by the first imaging pixel row of the plurality of imaging pixel rows.

8. The spectral imaging system of any of claims 1-7, wherein the multivariate optical element comprises a first multivariate optical element, the reference filter comprises a first reference filter, and the spectral imaging system further comprises:

a second reference filter optically coupled to a third imaging pixel row and;

a second multivariate optical element optically coupled to a fourth imaging pixel row of the plurality of imaging pixel rows, wherein:

the second imaging pixel row is positioned between the first imaging pixel row and the third imaging pixel row; and

the third imaging pixel row is positioned between the second imaging pixel row and the fourth imaging pixel row.

9. The spectral imaging system of any of claims 1-8, wherein the reference filter comprises a linear variable filter.

10. The spectral imaging system of any of claims 1-9, further comprising a conveyer system having a conveyer belt rotatably coupled to one or more conveyer rollers, wherein the conveyer belt and the focal plane array are positioned such that an imaging pathway extends between the conveyer belt and the focal plane array.

11. A method comprising:

generating a reference signal regarding a first portion of the specimen sample using a spectral imaging system, the spectral imaging system comprising:

a plurality of imaging pixels comprising a first imaging pixel and a second imaging pixel;

a reference filter optically coupled to the first imaging pixel; and

a multivariate optical element optically coupled to the second imaging pixel; wherein the first portion of the specimen sample is optically aligned with the first imaging pixel such that light traverses the reference filter before irradiating the first imaging pixel, thereby generating the reference signal;

optically aligning the first portion of the specimen sample with the second imaging pixel such that light traverses the multivariate optical element before irradiating the second imaging pixel; and

generating a spectral signal upon irradiation of light onto the second imaging pixel.

12. The method of claim 11, further comprising:

receiving the reference signal and the spectral signal at an imaging controller communicatively coupled to the first imaging pixel and the second imaging pixel;

generating, using the imaging controller, reference image data regarding the first portion of the specimen sample based on the reference signal and spectral image data regarding the first portion of the specimen sample based on the spectral signal;

comparing the reference image data and the spectral image data; and

determining a target spectral signature of first portion of the specimen sample based on the comparison between the reference image data and the spectral image data.

13. The method of claim 12, further comprising comparing the target spectral signature of the first portion of the specimen sample with a baseline spectral signature of the first portion of the specimen sample.

14. The method of any of claims 11-13, wherein the spectral imaging system further comprises: a focal plane array, wherein:

the focal plane array comprises a plurality of imaging pixel rows; each imaging pixel row of the plurality of imaging pixel rows comprises two or more individual imaging pixels; and

the plurality of imaging pixel rows comprise a first imaging pixel row that includes the first imaging pixel and a second imaging pixel row that includes the second imaging pixel, wherein:

the reference filter is optically coupled to the first imaging pixel row of the focal plane array; and

the multivariate optical element is optically coupled to the second imaging pixel row of the focal plane array.

15. The method of claim 14, wherein optically aligning the first portion of the specimen sample with the second imaging pixel comprises translating the focal plane array and the specimen sample relative to each other.

16. The method of claim 14, wherein the spectral imaging system further comprises:

an aperture; and

imaging optics positioned between and optically coupled to the aperture and the plurality of imaging pixels, wherein the imaging optics are configured to direct light from the aperture onto one or more of the plurality of imaging pixels, wherein:

the reference filter is positioned between the imaging optics and the first imaging pixel; and

the multivariate optical element is positioned between the imaging optics and the second imaging pixel.

17. The method of claim 16, wherein the imaging optics comprise a translatable optical component and optically aligning the first portion of the specimen sample with the second imaging pixel comprises translating the translatable optical component of the imaging optics to direct light onto the second imaging pixel.

18. A spectral imaging system comprising:

an aperture;

a plurality of imaging pixels comprising a first imaging pixel and a second imaging pixel; imaging optics positioned between and optically coupled to the aperture and the plurality of imaging pixels, wherein the imaging optics are configured to direct light from the aperture onto one or more of the plurality of imaging pixels;

a reference filter optically coupled to the first imaging pixel and positioned between the imaging optics and the first imaging pixel; and

a multivariate optical element optically coupled to the second imaging pixel and positioned between the imaging optics and the second imaging pixel.

19. The spectral imaging system of claim 18, further comprising a housing wherein:

the aperture is located on the housing; and

the plurality of imaging pixels, the imaging optics, the reference filter, and the multivariate optical element are each housed within the housing.

20. The spectral imaging system of claim 18, wherein the imaging optics comprise a translatable optical component configured to selectively direct light onto the first imaging pixel and the second imaging pixel.