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1. (WO2018101723) NOVEL FUNCTIONALLY ENHANCED MESENCHYMAL PROGENITOR CELLS, ANTI-INFLAMMATORY CELL THERAPEUTIC AGENT COMPOSITION CONTAINING SAME, AND MESENCHYMAL PROGENITOR CELL PREPARATION METHOD
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Pub. No.: WO/2018/101723 International Application No.: PCT/KR2017/013766
Publication Date: 07.06.2018 International Filing Date: 29.11.2017
IPC:
A61K 35/545 ,A61K 35/12 (2006.01) ,A61K 35/35 ,A61K 35/32 (2006.01) ,A61K 35/34 (2006.01) ,C12N 5/0735 (2010.01) ,C12N 5/074 (2010.01) ,C12N 5/077 (2010.01)
[IPC code unknown for A61K 35/545]
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
12
Materials from mammals or birds
[IPC code unknown for A61K 35/35]
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
12
Materials from mammals or birds
32
Bones; Tendons; Teeth; Cartilage
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
12
Materials from mammals or birds
34
Muscles; Heart
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07
Animal cells or tissues
071
Vertebrate cells or tissues, e.g. human cells or tissues
073
Embryonic cells or tissues; Foetal cells or tissues
0735
Embryonic stem cells; Embryonic germ cells
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07
Animal cells or tissues
071
Vertebrate cells or tissues, e.g. human cells or tissues
074
Adult stem cells
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07
Animal cells or tissues
071
Vertebrate cells or tissues, e.g. human cells or tissues
077
Mesenchymal cells, e.g. bone cells, cartilage cells, marrow stromal cells, fat cells or muscle cells
Applicants:
주식회사 미래셀바이오 MIRAECELLBIO. CO., LTD [KR/KR]; 서울시 광진구 아차산로 288, 2층 (자양동, 대흥빌딩) (Daeheung Building, Jayang-dong) 2th Floor, 288, Achasan-ro, Gwangjin-gu Seoul 05066, KR
Inventors:
정형민 CHUNG, Hyung Min; KR
홍기성 HONG, Ki Sung; KR
신정민 SHIN, Jeong Min; KR
Agent:
특허법인 무한 MUHANN PATENT & LAW FIRM; 서울시 강남구 언주로 560, 8층 (역삼동, 진영빌딩) 8F, Jinyoung Bldg., 560, Eonju-ro, Gangnam-gu, Seoul 06144, KR
Priority Data:
10-2016-016358402.12.2016KR
10-2016-016358602.12.2016KR
10-2017-010699424.08.2017KR
Title (EN) NOVEL FUNCTIONALLY ENHANCED MESENCHYMAL PROGENITOR CELLS, ANTI-INFLAMMATORY CELL THERAPEUTIC AGENT COMPOSITION CONTAINING SAME, AND MESENCHYMAL PROGENITOR CELL PREPARATION METHOD
(FR) NOUVELLES CELLULES PROGÉNITRICES MÉSENCHYMATEUSES FONCTIONNELLEMENT AMÉLIORÉES, COMPOSITION D'AGENT THÉRAPEUTIQUE CELLULAIRE ANTI-INFLAMMATOIRE LES CONTENANT, ET PROCÉDÉ DE PRÉPARATION DE CELLULES PROGÉNITRICES MÉSENCHYMATEUSES
(KO) 기능성이 향상된 신규 간엽성 전구세포, 이를 포함하는 항염증용 세포치료제 조성물 및 간엽성 전구세포의 제조방법
Abstract:
(EN) One embodiment of the present invention provides novel functionally enhanced mesenchymal progenitor cells overexpressing epidermal growth factor receptor (EGF-R) in comparison with mesenchymal stem cells (MSCs), and downexpressing cluster differentiation 95 (CD95) in comparison with the MSCs.
(FR) Un mode de réalisation de la présente invention concerne de nouvelles cellules progénitrices mésenchymateuses fonctionnellement améliorées surexprimant le récepteur du facteur de croissance épidermique (EGF-R) par comparaison avec des cellules souches mésenchymateuses (CSM), et sous-exprimant le cluster de différenciation 95 (CD95) par comparaison avec les CSM.
(KO) 본 발명의 일 실시예는 중간엽 줄기세포(MSC, Mesenchymal Stem Cell)에 비해 표피성장인자 수용체(EGF-R, Epidermal Growth Factor Receptor)를 과발현하고, 중간엽 줄기세포에 비해 CD95(Cluster Differentiation 95)를 저발현하는, 기능성이 향상된 신규 간엽성 전구세포를 제공한다.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)