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1. (WO2018101723) NOVEL FUNCTIONALLY ENHANCED MESENCHYMAL PROGENITOR CELLS, ANTI-INFLAMMATORY CELL THERAPEUTIC AGENT COMPOSITION CONTAINING SAME, AND MESENCHYMAL PROGENITOR CELL PREPARATION METHOD
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/101723    International Application No.:    PCT/KR2017/013766
Publication Date: 07.06.2018 International Filing Date: 29.11.2017
IPC:
A61K 35/545, A61K 35/12 (2006.01), A61K 35/35, A61K 35/32 (2006.01), A61K 35/34 (2006.01), C12N 5/0735 (2010.01), C12N 5/074 (2010.01), C12N 5/077 (2010.01)
Applicants: MIRAECELLBIO. CO., LTD [KR/KR]; (Daeheung Building, Jayang-dong) 2th Floor, 288, Achasan-ro, Gwangjin-gu Seoul 05066 (KR)
Inventors: CHUNG, Hyung Min; (KR).
HONG, Ki Sung; (KR).
SHIN, Jeong Min; (KR)
Agent: MUHANN PATENT & LAW FIRM; (Myeonglim Building, Nonhyeon-dong) 5th Floor, 9 Hakdong-ro 3-gil Gangnam-gu Seoul 06044 (KR)
Priority Data:
10-2016-0163584 02.12.2016 KR
10-2016-0163586 02.12.2016 KR
10-2017-0106994 24.08.2017 KR
Title (EN) NOVEL FUNCTIONALLY ENHANCED MESENCHYMAL PROGENITOR CELLS, ANTI-INFLAMMATORY CELL THERAPEUTIC AGENT COMPOSITION CONTAINING SAME, AND MESENCHYMAL PROGENITOR CELL PREPARATION METHOD
(FR) NOUVELLES CELLULES PROGÉNITRICES MÉSENCHYMATEUSES FONCTIONNELLEMENT AMÉLIORÉES, COMPOSITION D'AGENT THÉRAPEUTIQUE CELLULAIRE ANTI-INFLAMMATOIRE LES CONTENANT, ET PROCÉDÉ DE PRÉPARATION DE CELLULES PROGÉNITRICES MÉSENCHYMATEUSES
(KO) 기능성이 향상된 신규 간엽성 전구세포, 이를 포함하는 항염증용 세포치료제 조성물 및 간엽성 전구세포의 제조방법
Abstract: front page image
(EN)One embodiment of the present invention provides novel functionally enhanced mesenchymal progenitor cells overexpressing epidermal growth factor receptor (EGF-R) in comparison with mesenchymal stem cells (MSCs), and downexpressing cluster differentiation 95 (CD95) in comparison with the MSCs.
(FR)Un mode de réalisation de la présente invention concerne de nouvelles cellules progénitrices mésenchymateuses fonctionnellement améliorées surexprimant le récepteur du facteur de croissance épidermique (EGF-R) par comparaison avec des cellules souches mésenchymateuses (CSM), et sous-exprimant le cluster de différenciation 95 (CD95) par comparaison avec les CSM.
(KO)본 발명의 일 실시예는 중간엽 줄기세포(MSC, Mesenchymal Stem Cell)에 비해 표피성장인자 수용체(EGF-R, Epidermal Growth Factor Receptor)를 과발현하고, 중간엽 줄기세포에 비해 CD95(Cluster Differentiation 95)를 저발현하는, 기능성이 향상된 신규 간엽성 전구세포를 제공한다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Korean (KO)
Filing Language: Korean (KO)