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1. (WO2018101684) LACTOBACILLUS REUTERI CH53 STRAIN WITH HIGH PRODUCTION OF 1,3-PROPANDIOL FROM GLYCEROL AND USE THEREOF

Pub. No.:    WO/2018/101684    International Application No.:    PCT/KR2017/013587
Publication Date: Fri Jun 08 01:59:59 CEST 2018 International Filing Date: Tue Nov 28 00:59:59 CET 2017
IPC: C12N 1/20
C12P 7/18
A61K 8/34
A61K 8/99
A61Q 19/00
C12R 1/225
Applicants: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
한국생명공학연구원
ACTIVON CO., LTD.
주식회사 엑티브온
Inventors: KIM, Chul Ho
김철호
OH, Baek Rock
오백록
SEO, Jeong-Woo
서정우
HEO, Sun-Yeon
허선연
JU, Jung Hyun
주정현
Title: LACTOBACILLUS REUTERI CH53 STRAIN WITH HIGH PRODUCTION OF 1,3-PROPANDIOL FROM GLYCEROL AND USE THEREOF
Abstract:
The present invention relates to a Lactobacillus reuteri CH53 strain with high production of 1,3-propandiol from glycerol and the use thereof. The Lactobacillus reuteri CH53 strain of the present invention was found to be able to convert glycerol or crude glycerol to a high concentration of 1,3-propandiol at very high yield. Hence, the Lactobacillus reuteri CH53 strain according to the present invention, which is a lactic acid bacteria showing high production of 1,3-propandiol, is a kind of Generally Recognized As Safe (GRAS) lactic acid bacteria. If used for producing 1,3-propandiol from crude glycerol, the strain, unlike conventional GMO strains, is safe for the human body and can provide the advantage of resource recycling in terms of the environment, thus being useful for related industries.