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1. (WO2018101448) METHOD OF TREATING CANCER USING ANTI-CCR4 ANTIBODY AND ANTI-PD-1 ANTIBODY
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Pub. No.: WO/2018/101448 International Application No.: PCT/JP2017/043200
Publication Date: 07.06.2018 International Filing Date: 30.11.2017
IPC:
A61K 39/395 (2006.01) ,C07K 16/28 (2006.01) ,A61K 39/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
28
against receptors, cell surface antigens or cell surface determinants
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
Applicants:
KYOWA HAKKO KIRIN CO., LTD. [JP/JP]; 1-6-1, Otemachi, Chiyoda-ku, Tokyo 1008185, JP
ONO PHARMACEUTICAL CO., LTD. [JP/JP]; 1-5, Doshomachi 2-chome, Chuo-ku, Osaka-shi, Osaka 5148526, JP
BRISTOL MYERS-SQUIBB, COMPANY [US/US]; Route 206 & Province Line Road, Princeton, New Jersey 08540, US
Inventors:
KAWAKAMI Tetsuyoshi; JP
OHYAMA Yukiya; JP
GEMMOTO Kazuto; JP
KORMAN, Alan J.; US
LONBERG Nils; US
CHENG Shinta; US
AVERBUCH, Steven D.; US
MARSHALL Margaret; US
HEALY Denis; US
Agent:
EIKOH PATENT FIRM, P.C.; Toranomon East Bldg. 10F, 7-13, Nishi-Shimbashi 1-chome, Minato-ku, Tokyo 1050003, JP
Priority Data:
62/428,46830.11.2016US
62/554,48605.09.2017US
Title (EN) METHOD OF TREATING CANCER USING ANTI-CCR4 ANTIBODY AND ANTI-PD-1 ANTIBODY
(FR) MÉTHODE DE TRAITEMENT DU CANCER À L'AIDE D'UN ANTICORPS ANTI-CCR4 ET D'UN ANTICORPS ANTI-PD-1
Abstract:
(EN) A method of treating cancer comprising administering an anti-CC-chemokine receptor 4 (CCR4) antibody and an anti-programmed death-1 (PD-1) antibody to a subject is provided. Also provided is a composition or kit for use in treating a cancer comprising an anti-CCR4 antibody and an anti-PD-1 antibody.
(FR) L'invention concerne une méthode de traitement du cancer comprenant l'administration d'un anticorps du récepteur 4 de la chimokine anti-CC (CCR4) et d'un anticorps anti-mort programmée 1 (PD-1) à un sujet. L'invention concerne également une composition ou une trousse destinée à être utilisée dans le traitement d'un cancer comprenant un anticorps anti-CCR4 et un anticorps anti-PD-1.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)