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1. (WO2018100780) TARGET SUBSTANCE DETECTION DEVICE AND TARGET SUBSTANCE DETECTION METHOD

Pub. No.:    WO/2018/100780    International Application No.:    PCT/JP2017/023038
Publication Date: Fri Jun 08 01:59:59 CEST 2018 International Filing Date: Fri Jun 23 01:59:59 CEST 2017
IPC: G01N 21/27
G01N 21/41
Applicants: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
国立研究開発法人産業技術総合研究所
Inventors: YASUURA Masato
安浦 雅人
FUJIMAKI Makoto
藤巻 真
ASHIBA Hiroki
芦葉 裕樹
SHIMA Takayuki
島 隆之
Title: TARGET SUBSTANCE DETECTION DEVICE AND TARGET SUBSTANCE DETECTION METHOD
Abstract:
[Problem] To detect a target substance efficiently and with a high degree of accuracy. [Solution] This target substance detection device 1 comprises: a liquid sample introduction plate 2 formed from a light-transparent plate and which, when a liquid sample containing a target substance and magnetic particles is introduced onto the surface, allows transmitted light shone from the rear side to propagate as propagated light above the surface; a rear-side light-shining unit 3 which can shine the light from the rear side; a first magnetic field application unit 4 which is positioned on the surface side and which moves the aggregates in the liquid sample which has been introduced to the surface in a direction away from the liquid sample introduction plate 2 by applying a magnetic field; and an optical signal detection unit 5 which can detect signal changes in the optical signal before and after the application of the magnetic field by the first magnetic field application unit 4. The optical signal detection unit 5 can detect, from among optical signals and as signals to which signal changes apply, only optical signals on the basis of aggregates obtained by two or more magnetic particles bonding to a single target substance.