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1. (WO2018100724) SPOT ARRAY SUBSTRATE, NUCLEIC ACID ANALYSIS METHOD, AND NUCLEIC ACID ANALYSIS DEVICE

Pub. No.:    WO/2018/100724    International Application No.:    PCT/JP2016/085823
Publication Date: Fri Jun 08 01:59:59 CEST 2018 International Filing Date: Fri Dec 02 00:59:59 CET 2016
IPC: C12M 1/00
C12N 15/09
C12Q 1/68
G01N 21/64
G01N 33/50
G01N 37/00
Applicants: HITACHI HIGH-TECHNOLOGIES CORPORATION
株式会社日立ハイテクノロジーズ
Inventors: ITABASHI Naoshi
板橋 直志
YOKOI Takahide
横井 崇秀
UEMATSU Chihiro
植松 千宗
MIGITAKA Sonoko
右高 園子
Title: SPOT ARRAY SUBSTRATE, NUCLEIC ACID ANALYSIS METHOD, AND NUCLEIC ACID ANALYSIS DEVICE
Abstract:
The present invention improves throughput of nucleic acid analysis by preventing a reduction in S/B associated with increasingly higher integration of a spot array substrate. The present invention proposes a spot array substrate for nucleic acid analysis, in which spots are disposed in an array arrangement on the surface of a first material, while a region other than where the spots exist is covered with a second material, wherein a surface area increasing structure in which the height varies in a direction perpendicular to the substrate is formed at the portion where the spots exist so that the actual surface area becomes greater than the area defined by the outlines of the spots as viewed from above the substrate.