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1. (WO2018100574) METHODS OF TREATING LIVER TOXICITY AND DISORDERS

Pub. No.:    WO/2018/100574    International Application No.:    PCT/IL2017/051297
Publication Date: Fri Jun 08 01:59:59 CEST 2018 International Filing Date: Wed Nov 29 00:59:59 CET 2017
IPC: A61K 31/167
A61K 45/06
A61P 1/16
Applicants: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
Inventors: ELINAV, Eran
SEGAL, Eran
Title: METHODS OF TREATING LIVER TOXICITY AND DISORDERS
Abstract:
A method of reducing the liver toxicity of a liver-damaging agent is disclosed. The method comprises administering to the subject: (i) the liver-damaging agent; and (ii) an agent which alters the circadian rhythmicity of microbes of the gut microbiome of the subject.