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1. (WO2018100434) PREPARATION OF SOLID CYCLODEXTRIN COMPLEXES FOR OPHTHALMIC ACTIVE PHARMACEUTICAL INGREDIENT DELIVERY
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/100434    International Application No.:    PCT/IB2017/001659
Publication Date: 07.06.2018 International Filing Date: 29.11.2017
IPC:
A61K 47/69 (2017.01), A61K 9/00 (2006.01)
Applicants: OCULIS EHF [IS/IS]; Grandagardur 16 IS-101 Reykjavik (IS)
Inventors: LOFTSSON, Thorsteinn; (IS).
FULOP, Zoltan; (IS)
Priority Data:
62/427,737 29.11.2016 US
Title (EN) PREPARATION OF SOLID CYCLODEXTRIN COMPLEXES FOR OPHTHALMIC ACTIVE PHARMACEUTICAL INGREDIENT DELIVERY
(FR) PRÉPARATION DE COMPLEXES SOLIDES DE CYCLODEXTRINE PERMETTANT UNE ADMINISTRATION DE SUBSTANCE PHARMACEUTIQUE ACTIVE OPHTALMIQUE
Abstract: front page image
(EN)The present disclosure relates to ophthalmic compositions containing solid complexes of active pharmaceutical ingredient and cyclodextrin, to their method of preparation and their uses. The compositions can include an active agent drug/cyclodextrin complex substantially dissolved in an aqueous eye drop vehicle. The ophthalmic composition is generally in the form of a microsuspension including an active agent complex having a diameter of less than about 100 µm.
(FR)La présente invention concerne des compositions ophtalmiques contenant des complexes solides de substance pharmaceutique active et de cyclodextrine, leur méthode de préparation et leurs utilisations. Les compositions peuvent comprendre un complexe médicament à principe actif/cyclodextrine sensiblement dissout dans un vecteur aqueux de gouttes ophtalmiques. La composition ophtalmique se présente globalement sous la forme d'une microsuspension comprenant un complexe de principes actifs ayant un diamètre inférieur à environ 100 µm.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)