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1. (WO2018100070) BICYCLIC AMIDE COMPOUNDS AND METHODS OF USE THEREOF

Pub. No.:    WO/2018/100070    International Application No.:    PCT/EP2017/080996
Publication Date: Fri Jun 08 01:59:59 CEST 2018 International Filing Date: Fri Dec 01 00:59:59 CET 2017
IPC: C07D 471/04
C07D 487/04
C07D 491/04
C07D 491/048
C07D 519/00
A61K 31/4196
A61K 31/5383
A61K 31/4375
A61K 31/439
A61P 29/00
A61P 9/00
Applicants: F. HOFFMANN-LA ROCHE AG
GENENTECH, INC.
Inventors: PATEL, Snahel
HAMILTON, Gregory
ZHAO, Guiling
CHEN, Huifen
Title: BICYCLIC AMIDE COMPOUNDS AND METHODS OF USE THEREOF
Abstract:
The invention provides novel compounds having the general formula I: (I) wherein R1, R2, the A ring and the B ring are as described herein, pharmaceutical compositions including the compounds and methods of using the compounds.