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1. (WO2018100036) ANALYSIS OF ANTI-ERYTHROCYTE ANTIBODY IN THE PRESENCE OF ANTIBODY DIRECTED AGAINST A SURFACE-BOUND ERYTHROCYTE ANTIGEN
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Pub. No.: WO/2018/100036 International Application No.: PCT/EP2017/080926
Publication Date: 07.06.2018 International Filing Date: 30.11.2017
IPC:
G01N 33/80 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
80
involving blood groups or blood types
Applicants:
IMUSYN GMBH & CO. KG [DE/DE]; Feodor-Lynen-Str. 5 30625 Hannover, DE
Inventors:
SCHNEEWEISS, Clemens; DE
GRÜGER, Daniela; DE
Agent:
TARUTTIS, Stefan; DE
Priority Data:
16201819.601.12.2016EP
17150738.709.01.2017EP
Title (EN) ANALYSIS OF ANTI-ERYTHROCYTE ANTIBODY IN THE PRESENCE OF ANTIBODY DIRECTED AGAINST A SURFACE-BOUND ERYTHROCYTE ANTIGEN
(FR) ANALYSE D’ANTICORPS ANTI-ÉRYTHROCYTE EN PRÉSENCE D’UN ANTICORPS DIRIGÉ CONTRE UN ANTIGÈNE DE SURFACE D’ÉRYTHROCYTE
Abstract:
(EN) An analytical process for detecting antibody in human blood serum, which antibody is directed against blood group antigen, wherein the serum contains an additional antibody directed against a surface antigen, by contacting the serum to be analysed with blood cell membranes, which naturally bear surface blood group antigens, followed by detection of agglutination which indicated the presence of antibody directed against at least one surface antigen of the blood cell membranes. The agglutination reaction caused by the additional antibody is prevented, allowing the detection of anti-blood group antibody.
(FR) La présente invention concerne un procédé analytique pour détecter un anticorps dans le sérum sanguin humain, ledit anticorps étant dirigé contre un antigène de groupe sanguin, le sérum contenant un anticorps supplémentaire dirigé contre un antigène de surface, par mise en contact du sérum à analyser avec des membranes de cellules sanguines, qui comportent naturellement des antigènes de groupe sanguin de surface, suivi d’une détection d’agglutination qui indique la présence d’un anticorps dirigé contre au moins un antigène de surface des membranes de cellules sanguines. La réaction d’agglutination causée par l’anticorps supplémentaire est inhibée, de façon à permettre la détection d’un anticorps de groupe sanguin.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)