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1. (WO2018100017) METHOD AND SYSTEM FOR TREATING BIOLOGICAL SAMPLES

Pub. No.:    WO/2018/100017    International Application No.:    PCT/EP2017/080894
Publication Date: Fri Jun 08 01:59:59 CEST 2018 International Filing Date: Fri Dec 01 00:59:59 CET 2017
IPC: G01N 1/44
G01N 1/30
C12Q 1/6806
G01N 33/53
Applicants: VENTANA MEDICAL SYSTEMS, INC.
F. HOFFMANN-LA ROCHE AG
Inventors: BARNETT, Heidi
HANNON, Andrew M.
PHILLIPS-PORTILLO, James E.
Title: METHOD AND SYSTEM FOR TREATING BIOLOGICAL SAMPLES
Abstract:
Disclosed are methods and systems for unmasking protein antigens and nucleic acid targets in fixed cell samples using UV light. In some embodiments, UV light exposure is combined with other unmasking methods and agents to help ensure difficult to unmask molecular entities are reliably rendered detectable.